NF-κB信号通路与多发性骨髓瘤发病机制的相关性及靶向治疗作用的研究进展  

Research Progress in the Correlation between NF-κB Signaling Pathway and the Pathogenesis of Multiple Myeloma,and the Targeted Therapeutic Effects

作　　者：温少瑾[1] 杨焕莹 孙凤歧[1] 申小惠[1] WEN Shaojin;YANG Huanying;SUN Fengqi;SHEN Xiaohui(Gansu Provincial Hospital of Traditional Chinese Medicine,Lanzhou 730050,China;Tianjin Hedong District Hospital of Traditional Chinese Medicine,Tianjin 300162,China)

机构地区：[1]甘肃省中医院,甘肃兰州730050 [2]天津市河东区中医医院,天津300162

出　　处：《西部中医药》2024年第7期97-102,共6页Western Journal of Traditional Chinese Medicine

基　　金：甘肃省自然科学基金(22JR5RA623)。

摘　　要：通过对核因子kappa B信号通路进行阐述,分析其与多发性骨髓瘤(multiple myeloma,MM)发病机制的关系,及对其靶向治疗的相关研究进行综述,分析其现存的问题和未来发展的方向,以期为MM的靶向治疗提供新思路。By illustrating the NF-κB signalling pathway,we analysed its correlation with the pathogenesis of multiple myeloma(MM),summarized the studies related to its targeted therapy,and explored the existing problems and the future development direction,so as to provide new thinking for the targeted therapy of MM.

关 键 词：多发性骨髓瘤 NF-ΚB信号通路 靶向治疗 

分 类 号：R738.1[医药卫生—肿瘤]