颅内动脉瘤血流导向装置治疗后迟发性脑实质出血  

Delayed intraparenchymal hemorrhage following treatment of intracranial aneurysms with flow diverter

作　　者：周子涵 吴勇强[2,3,4] 郭庚 Zhou Zihan;Wu Yongqiang;Guo Geng(Department of Neurosurgery,the First Hospital of Shanxi Medical University,Taiyuan 030001,China;Cerebrovascular Disease Center,the First Hospital of Shanxi Medical University,Taiyuan 030001,China;Research Center for Cerebrovascular Diseases,Shanxi Medical University,Taiyuan 030001,China;Department of Neurosurgery,Xinghualing District Central Hospital,Taiyuan 030009,China;Emergency Medical Center of the First Hospital of Shanxi Medical University,Taiyuan 030001,China)

机构地区：[1]山西医科大学第一医院神经外科,太原030001 [2]山西医科大学第一医院脑血管病中心,太原030001 [3]山西医科大学脑血管病研究中心,太原030001 [4]太原市杏花岭区中心医院神经外科,太原030009 [5]山西医科大学第一医院急诊医学中心,太原030001

出　　处：《国际脑血管病杂志》2024年第3期227-232,共6页International Journal of Cerebrovascular Diseases

基　　金：山西智能大数据产业技术创新研究院科研基金项目(SIBD-2020-YL0052)。

摘　　要：血流导向装置(flow diverter,FD)是颅内动脉瘤的血管内治疗方式之一。迟发性脑实质出血(delayed intraparenchymal hemorrhage,DIPH)是FD术后的一种严重并发症,可能导致严重神经功能恶化、转归不良甚至死亡。DIPH的发生机制目前尚不完全清楚,可能与动脉瘤的形态学特征、血流动力学改变、术后缺血性病灶的出血性转化、药物治疗方案以及免疫炎症反应等因素相关。文章对颅内动脉瘤FD术后DIPH进行综述,以期为围手术期管理提供参考。Flow director(FD)is one of endovascular treatment methods for intracranial aneurysms.Delayed intraparenchymal hemorrhage(DIPH)is a serious complication after FD,which may lead to severe neurological deterioration,poor outcome,and even death.The mechanism of DIPH is currently not fully understood and may be associated with factors such as the morphological characteristics of the aneurysm,hemodynamic changes,hemorrhagic transformation of postoperative ischemic lesions,drug treatment regimens,and immune inflammatory response.This article reviews the DIPH following treatment of intracranial aneurysms with FD,in order to provide reference for perioperative management.

关 键 词：颅内动脉瘤 血管内手术 栓塞 治疗性 支架 脑出血 手术后并发症 

分 类 号：R743[医药卫生—神经病学与精神病学]