吲哚菁绿荧光造影技术在腹腔镜结直肠癌根治术中的应用  

Application of indocyanine green fluorescence imaging technology in laparoscopic radical resection of colorectal cancer

作　　者：林建展 阎伟 官文龙[1] 于林枫 刘超然 朱安龙[1] Lin Jianzhan;Yan Wei;Guan Wenlong;Yu Linfeng;Liu Chaoran;Zhu Anlong(Department of Colorectal Surgery,The First Affiliated Hospital of Harbin Medical University,Harbin 150001,China)

机构地区：[1]哈尔滨医科大学附属第一医院结直肠外科,哈尔滨150001

出　　处：《中华消化外科杂志》2024年第6期876-882,共7页Chinese Journal of Digestive Surgery

基　　金：黑龙江省普通本科高等学校青年创新人才培养计划(31011180065)。

摘　　要：随着腹腔镜手术的日趋成熟,腹腔镜结直肠癌根治术在结直肠外科得到广泛应用.术中触觉缺失情况下对结直肠肿瘤及切缘难以进行准确定位;在保证肠吻合口足够血流灌注的前提下,进而有效降低肠吻合口漏的发生率等问题已成为限制腹腔镜结直肠癌根治术开展的障碍.吲哚菁绿荧光造影(ICG-FI)技术的应用有望为上述问题提供切实可行的处理方案.ICG-FI技术可在腹腔镜下完成对结直肠肿瘤的精确定位、术中肠吻合口血供的评估、淋巴系统显像、结直肠癌肝转移灶的检测、术中盆腔自主神经及输尿管的保护等操作,从而进一步提高腹腔镜结直肠癌根治术的手术质量.然而,ICG-FI技术在结直肠外科的临床应用时间较短,可供借鉴的指南及共识较少,尚处在探索及经验积累阶段.因此,笔者查阅国内外文献,根据吲哚菁绿在结直肠癌手术中不同应用类型,对相关文献进行回顾和整理,以期为该技术的临床应用提供参考.With the increasing maturity of laparoscopic surgery,laparoscopic radical resec-tion of colorectal cancer has been widely used in colorectal surgery.Accurate localization of colorectal tumors and surgical margins in the absence of tactile sensation during surgery,ensuring sufficient blood flow perfusion at the anastomotic site and effectively reducing the incidence of anastomotic leakage have become barriers to the development of laparoscopic radical resection of colorectal cancer.The application of indocyanine green fluorescence imaging(ICG-FI)technology is expected to provide feasible solutions to the above-mentioned problems.Through this technology,accurate localization of colorectal tumors,evaluation of blood supply to the anastomotic site,lymphatic system imaging,detection of colorectal liver metastases,and protection of pelvic autonomous nerves and ureters can be achieved during laparoscopic surgery,thereby further improving the surgical quality of laparoscopic radical resection of colorectal cancer.However,the clinical application of ICG-FI technology in colorectal surgery is relatively short,which is still in the stage of exploration and experience accumulation,and there are few guideline or consensus available for reference.Therefore,the authors aim to provide a reference for the clinical application of this technology by reviewing and summarizing relevant literature based on different application types of ICG in colo-rectal cancer surgery.

关 键 词：结直肠肿瘤 外科 吲哚菁绿 结直肠癌根治术 荧光造影技术 腹腔镜检查 

分 类 号：R735.34[医药卫生—肿瘤]