荧光原位杂交技术在血液肿瘤中的应用规范(2024年版)  

Application standard of fluorescence in situ hybridization in hematologic neoplasms(2024 version)

作　　者：中国抗癌协会血液病转化医学专业委员会 中国老年医学学会病理学分会 中华医学会血液学分会 王欣 卢朝辉[3] 汝昆 金洁 贡铁军[6] 蔺亚妮 Committee of Translational Medicine in Hematology,China Anti-Cancer Association;Pathology Branch of Chinese Geriatrics Society;Hematology Branch of Chinese Medical Association

机构地区：[1]不详 [2]山东第一医科大学附属省立医院血液科,济南250021 [3]北京协和医院 [4]山东省肿瘤医院病理检验特检中心,济南250117 [5]浙江大学附属第一医院 [6]哈尔滨市第一医院血液肿瘤研究中心,哈尔滨150010 [7]天津见康华美医学诊断中心

出　　处：《白血病．淋巴瘤》2024年第4期193-198,共6页Journal of Leukemia & Lymphoma

摘　　要：荧光原位杂交(FISH)技术是血液肿瘤诊疗的必要检测手段。该应用规范参考国内外权威资料,结合临床诊疗实践,基于不同临床用途总结了不同亚型血液肿瘤必要和推荐的检测指标,并阐述了FISH检测前、中、后各个环节的检测要点及质量控制要求,旨在实现血液肿瘤FISH检测临床应用的规范化和标准化,从而进一步提高诊疗水平。Fluorescence in situ hybridization(FISH)is an important testing tool for the diagnosis and treatment of hematologic neoplasms.With reference to the authoritative data at home and abroad,and combined with the clinical diagnosis and treatment practice,this application standard summarized the essential and recommended FISH tests tailored to various hematologic neoplasms based on distinct clinical setting,and emphasized the key detection points and quality control requirements throughout the pre-analysis,analysis and post-analysis phases of FISH detection.The aim is to standardize the clinical application of FISH detection in hematologic neoplasms,so as to further improve the precision diagnosis and treatment.

关 键 词：血液肿瘤 荧光原位杂交 质量控制 

分 类 号：R733[医药卫生—肿瘤]