精子发生中小非编码RNA的新见解  

New insights into small non-coding RNAs during spermatogenesis

作　　者：王鑫 张振翼 赵爽 刘默芳 Xin Wang;Zhen-Yi Zhang;Shuang Zhao;Mo-Fang Liu(Key Laboratory of Systems Health Science of Zhejiang Province,School of Life Science,Hangzhou Institute for Advanced Study,University of Chinese Academy of Sciences,Hangzhou 310024,China;New Cornerstone Science Laboratory,State Key Laboratory of Molecular Biology,State Key Laboratory of Cell Biology,Shanghai Key Laboratory of Molecular Andrology,Shanghai Institute of Biochemistry and Cell Biology,Center for Excellence in Molecular Cell Science,Chinese Academy of Sciences,University of Chinese Academy of Sciences,Shanghai 200031,China;School of Life Science and Technology,ShanghaiTech University,Shanghai 201210,China)

机构地区：[1]Key Laboratory of Systems Health Science of Zhejiang Province,School of Life Science,Hangzhou Institute for Advanced Study,University of Chinese Academy of Sciences,Hangzhou 310024,China [2]New Cornerstone Science Laboratory,State Key Laboratory of Molecular Biology,State Key Laboratory of Cell Biology,Shanghai Key Laboratory of Molecular Andrology,Shanghai Institute of Biochemistry and Cell Biology,Center for Excellence in Molecular Cell Science,Chinese Academy of Sciences,University of Chinese Academy of Sciences,Shanghai 200031,China [3]School of Life Science and Technology,ShanghaiTech University,Shanghai 201210,China

出　　处：《Science Bulletin》2024年第11期1581-1585,共5页科学通报（英文版）

基　　金：supported by the National Key R&D Program of China (2021YFC2700200 and 2022YFA1303300);National Natural Science Foundation of China (32330053,31830109,31821004,32271347,32101037 and 32071286);Science and Technology Commission of Shanghai Municipality (19JC1410200,21YF1452700 and 21ZR1470500);Zhejiang Provincial Natural Science Foundation of China (LZ23C050001);the Young Elite Scientist Sponsorship Program of the China Association for Science and Technology (2021QNRC001);the Research Funds of Hangzhou Institute for Advanced Study,UCAS(2023HIAS-Y022);the Foundation of Key Laboratory of Gene Engineering of the Ministry of Education;the New Cornerstone Science Foundation (NCI202329)。

摘　　要：Spermatogenesis is one of the most complicated cell differentiation processes in animals, which consists of mitosis, meiosis, and the post-meiotic phase of male germ cell development, i.e.,spermiogenesis. Mitosis is responsible for germline maintenance,while meiosis reduces the chromosome number by half and creates genetic diversity in the sperm.

关 键 词：精子发生 maintenance MITOSIS 

分 类 号：Q492.4[生物学—生理学]