抑郁症网络团体认知行为治疗的单盲随机对照研究  

A single-blind randomized controlled study of efficacy of internet-based group cognitive-behavioral therapy on major depressive disorder

作　　者：韩建芳 白延欣[1] 宝继英[1] 马军[1] 麻钰超 黄悦勤[2] 于东升[1] HAN Jianfang;BAI Yanxin;BAO Jiying;MA Jun;MA Yuchao;HUANG Yueqin;YU Dongsheng(Inner Mongolia Autonomous Region Brain Hospital,Inner Mongolia Autonomous Region Mental Health Center,Hohhot O10010,China;Peking University Sixth Hospital,Peking University Institute of Mental Health,NHC Key Laboratory of Mental Health(Peking University),National Clinical Research Center for Mental Disorders(Peking University Sixth Hospital),Beijing 100083,China)

机构地区：[1]内蒙古自治区脑科医院,内蒙古自治区精神卫生中心,呼和浩特010010 [2]北京大学第六医院,北京大学精神卫生研究所,国家卫生健康委员会精神卫生学重点实验室(北京大学),国家精神心理疾病临床医学研究中心(北京大学第六医院),北京100083

出　　处：《中国心理卫生杂志》2024年第8期660-665,共6页Chinese Mental Health Journal

基　　金：内蒙古自治区自然科学基金——首发抑郁症患者全病程管理模式的疗效研究(2019MS03038)。

摘　　要：目的:探讨网络团体认知行为治疗(IGCBT)对抑郁症(MDD)患者抑郁情绪、焦虑情绪的疗效。方法:招募MDD患者80例,随机分为IGCBT联合药物治疗组和单纯药物治疗对照组。在基线、治疗4周和8周后分别三次采用汉密尔顿抑郁量表(HAMD)、汉密尔顿焦虑量表(HAMA)进行盲法评估。结果:联合治疗组4周末HAMD、HAMA以及8周末HAMA的有效率均高于对照组(均P<0.05),联合治疗组、对照组在4周末、8周末时HAMD总分、HAMA总分均低于基线得分(均P<0.001),在基线、4周末、8周末,联合治疗组HAMD总分、HAMA总分均低于对照组得分(均P<0.01)。结论:本研究提示,网络团体认知行为治疗联合抗抑郁药物治疗比单纯使用药物治疗对患者抑郁情绪、焦虑情绪的缓解效果更好,且对焦虑情绪改善效果更佳。Objective:To explore the effects of internet-based group cognitive-behavioral therapy(IGCBT)on the depressive and anxiety symptoms in patients with major depressive disorder(MDD).Methods:Eighty patients with MDD were recruited and randomly divided into IGCBT combined drug therapy group and control group with drug therapy.Blind assessments were performed using the Hamilton Depression Scale(HAMD)and Hamilton Anxiety Scale(HAMA)three times at baseline,4 weeks after treatment and 8 weeks after treatment,respectively.Results:The effective rates of HAMD and HAMA at the end of the 4th and 8th week,and the effective rates of HAMA at the end of the 8th week were higher in the combined treatment group than those in the control group(Ps<0.05).The total scores of HAMD and HAMA in the combined treatment group and the control group were lower at the end of the 4th and 8th week than those at baseline(Ps<0.001).The total scores of HAMD and HAMA were lower in the combined treatment group than those in the control group at the baseline,4 weeks and 8 weeks after treatment(Ps<0.01).Conclusion:It suggests that internet-based group cognitive-behavioral therapy combined with antidepressant medication has a better effect on relieving depressive and anxiety symptoms in patients with major depressive disorder than drug therapy alone,and especially has a better effect on improving anxiety symptom.

关 键 词：网络团体认知行为治疗 抑郁症 抑郁 焦虑 

分 类 号：R749.41[医药卫生—神经病学与精神病学] R749.059[医药卫生—临床医学]