高脂血症性胰腺炎急性期临床特征分析及不同评分系统对疾病严重程度的预测价值  

Comparison of Clinical Features in Acute Stage of HyperlipidemicPancreatitis and the Predictive Value of Different Scoring Systems for Disease Severity

作　　者：周奕 张燕红 谭嘉圣 黄乐煊 袁敏婷 ZHOU Yi;ZHANG Yan-hong;TAN Jia-sheng;HUANG Le-xuan;YUANG Min-ting(Dongguan Songshan Lake Central Hospital,Dongguan,523326)

机构地区：[1]广东省东莞市松山湖中心医院消化内科,523326

出　　处：《岭南急诊医学杂志》2024年第3期227-229,240,共4页Lingnan Journal of Emergency Medicine

基　　金：广东省东莞市社会发展科技面上项目(20231800903742)。

摘　　要：目的:分析不同类型胰腺炎患者急性期临床发病特点及探讨不同评分系统对疾病进展的预测价值。方法:研究对象为2023年1月-2023年10月东莞市松山湖中心医院诊治的206例胰腺炎患者,按病因分为高脂血症性胰腺炎组121例(HTG-AP组)与非高脂血症性胰腺炎组85例(NHTG-AP组),比较两组急性期的临床特点,并采用多因素logistic回归分析比较不同评分系统对胰腺炎疾病进展预测价值。结果:两组以轻症胰腺炎为主,高脂血症性急性胰腺炎患者CRP、TG/HDL、LDL/HDL较非高脂血症性胰腺炎患者高,总胆红素、AST、甲状腺素低,两组差异具有统计学意义(P<0.05)。BISAP评分、改良Marshall评分可在疾病早期预测胰腺炎进展(P<0.05)。结论:高脂血症急性胰腺炎疾病年轻化,易复发,两组对比,高脂血症性胰腺炎炎症反应较非高脂血症性胰腺炎高,甲状腺素较非高脂血症性胰腺炎降低,疾病早期可应用BISAP评分、改良Marshall评分预测急性胰腺炎进展。Objective:To analyze the clinical characteristics of acute stage in patients with different types of pancre-atitis and explore the predictive value of different scoring systems for disease progression.Methods:A total of 206 pa-tients with pancreatitis diagnosed and treated in Guangdong Songshan Lake Central Hospital of Dongguan City from Janu-ary 2023 to October 2023 were selected,who were divided into 121 patients with hyperlipidemic pancreatitis group(HTG-AP group)and 85 patients with non-hyperlipidemic pancreatitis group(NHTG-AP group)according to their etiology.The clinical characteristics of the two groups at the acute stage were compared.Multivariate logistic regression analysis was used to compare the value of different scoring systems in predicting the progression of pancreatitis.Results:The patients with hyperlipidemic acute pancreatitis had higher CRP,TG/HDL and LDL/HDL than those with non-hyperlipidemic acute pancreatitis,and lower total bilirubin,AST and thyroxine,with statistical significance between the two groups(P<0.05).BISAP score and modified Marshall score could predict the progression of pancreatitis in the early stage of the disease(P<0.05).Conclusion:Hyperlipidemic acute pancreatitis is young and prone to recurrence.Compared with the two groups,hyperlipidemic pancreatitis has higher inflammatory response and lower thyroxine than non-hyperlipidemic pancreatitis.BISAP score and modified Marshall score can be used to predict the progression of acute pancreatitis in the early stage of the disease.

关 键 词：急性高脂血症性胰腺炎 急性期临床特征 胰腺炎评分系统 

分 类 号：R576[医药卫生—消化系统]