缺血性脑血管病血清尿酸水平与颈动脉不稳定斑块关系  

Relationship between Serum Uric Acid Levels and Unstable Carotid Plaques in Ischemic Cerebrovascular Disease

作　　者：崔敏[1] 杨超[1] CUI Min;YANG Chao(Affiliated Hospital of Beihua University,Jilin 132011,China)

机构地区：[1]北华大学附属医院,吉林吉林132011

出　　处：《北华大学学报（自然科学版）》2024年第4期488-491,共4页Journal of Beihua University（Natural Science）

基　　金：吉林省中医药科技项目(2023066)。

摘　　要：目的 探讨缺血性脑血管病血清尿酸水平与颈动脉不稳定斑块关系。方法 选择60例缺血性脑血管病患者,其中,短暂性脑缺血发作30例(短暂性脑缺血发作组);脑梗死30例(脑梗死组),测定两组患者的血清尿酸水平,分析缺血性脑血管病血清尿酸水平与颈动脉不稳定斑块的关系。结果 短暂性脑缺血发作组的血清尿酸水平显著低于脑梗死组(P<0.05)。Logtisic回归分析显示,血清尿酸水平升高是缺血性脑血管病患者斑块发生的危险因素(P<0.05)。随着斑块面积增大,血清尿酸水平升高(P<0.05)。结论 缺血性脑血管病血清尿酸水平与颈动脉不稳定斑块关系密切,血清尿酸水平是患者斑块发生的独立危险因素,通过早期监测血清尿酸水平,可更好地评估颈动脉斑块的不稳定性,为疾病早期诊治提供基础。Objective To explore the relationship between serum uric acid levels and unstable carotid artery plaques in ischemic cerebrovascular disease.Method Sixty patients with ischemic cerebrovascular disease were selected,among which 30 cases had transient ischemic attacks and assigned to the transient ischemic attack group;30 cases of cerebral infarction were assigned to the cerebral infarction group,and their serum uric acid levels were measured to analyze the relationship between serum uric acid levels in ischemic cerebrovascular disease and unstable carotid plaques.Result The serum uric acid levels of the transient ischemic attack group were significantly lower than those of the cerebral infarction group(P<0.05).Logtic regression analysis showed that elevated blood uric acid is a risk factor for plaque formation in patients with ischemic cerebrovascular disease(P<0.05).As the plaque area increases,serum uric acid increases(P<0.05).Conclusion There is a close relationship between serum uric acid levels and unstable carotid artery plaques in ischemic cerebrovascular disease.Serum uric acid level is an independent risk factor for plaque occurrence in patients.Early monitoring of serum uric acid can better evaluate carotid artery instability and provide a basis for early diagnosis and treatment of the disease.

关 键 词：缺血性脑血管病 血清尿酸水平 颈动脉不稳定斑块 

分 类 号：R743.32[医药卫生—神经病学与精神病学]