A case of herpesviral corneal endotheliitis presenting with corneal endothelial defect  

作　　者：Yan-Xia Chen Han Deng Xiao-Yun Ke Min Fu 

机构地区：[1]Department of Ophthalmology,Women and Children’s Hospital,School of Medicine,Xiamen University,Xiamen 361003,Fujian Province,China [2]Department of Ophthamology,Zhujiang Hosptial,Southern Medical University,Guangzhou 510280,Guangdong Province,China

出　　处：《International Journal of Ophthalmology(English edition)》2024年第7期1375-1378,共4页国际眼科杂志（英文版）

摘　　要：Dear Editor,Corneal endotheliitis,first reported in 1982 as an autoimmune disorder by Khodadoust and Attarzadeh[1],is now recognized to be frequently induced by viral infections,including varicella zoster virus(VZV),cytomegalovirus(CMV)and herpes simplex virus(HSV),that can cause inflammatory and immune-related injuries or direct damages to corneal endothelial cells[2-3].In cases with this type of endotheliitis of viral origin,manifestations may include conjunctival ciliary congestion or mixed congestion,corneal subepithelial bulla,localized corneal edema,keratic precipitates(KP)characteristic to the edema area,puckered posterior elastic lamina,mild anterior chamber reaction,intraocular pressure(IOP)elevation in presence of inflammation in trabecular meshwork,and endothelial decompensation[3-4].Accurate diagnosis of viral corneal endotheliitis is challenging due to its complex presentation,leading to a high misdiagnosis rate.To the best of our knowledge,there was no previous report of viral corneal endotheliitis presenting with corneal endothelial defects in the English literature.

关 键 词：CORNEAL INJURIES HERPES 

分 类 号：R772.2[医药卫生—眼科]