糖醇类甜味剂及其对机体影响的研究进展  

Research progress on sugar alcohol sweeteners and their effects on human body

作　　者：王梦 李晓永[1] 秦利[1] Wang Meng;Li Xiaoyong;Qin Li(Department of Endocrinology,Xinhua Hospital,Shanghai Jiaotong University,Shanghai 200092,China)

机构地区：[1]上海交通大学附属新华医院内分泌科,上海200092

出　　处：《中华临床营养杂志》2024年第3期186-192,共7页Chinese Journal of Clinical Nutrition

基　　金：上海市卫生健康委员会科研项目(202240107)。

摘　　要：糖醇类甜味剂作为一种替代糖,目前广泛应用于食品添加行业。世界卫生组织表示,长期摄入人工甜味剂可能对身体健康产生负面影响,但唯一例外的是由糖醇制成的甜味剂。因此,对糖醇类甜味剂的研究日益受到关注。随着研究的深入,发现糖醇类甜味剂与肠道菌群、糖脂代谢、心血管疾病和肿瘤关系密切。此外,近期亦有研究表明,某些糖醇是一种内源性代谢物,可预测多种疾病的发生风险。该文在介绍糖醇类甜味剂的基础上,系统综述了其对人体的影响及其机制研究进展,以期为该领域的研究提供参考。Sugar alcohol sweeteners are now widely used in the food additives industry as sugar substitutes.According to the World Health Organization,long-term intake of artificial sweeteners may have negative effects on health,but the only exception is sugar alcohols.As a result,researches on sugar alcohol sweeteners have gained increasing study interests in recent years.As the study progresses,it has been found that sugar alcohol sweeteners are closely related with gut microbes,lipid metabolism,cardiovascular disease and tumors.In addition,recent studies have also shown that some sugar alcohols are endogenous metabolites which can predict the risk of a variety of diseases.This review systematically details the effects of sugar alcohol sweeteners on human body and the underlying mechanisms,in order to provide a reference for the scientific research in this field.

关 键 词：糖醇类 甜味剂 吸收 代谢 

分 类 号：R587.1[医药卫生—内分泌]