乳腺微创旋切手术中肿瘤良恶性与临床病理特征相关性分析  

Correlation analysis of benign,malignant and clinicopathological features of breast tumors during minimally invasive rotational resection

作　　者：李晓欧 祁晓莉 张立英 LI Xiao-ou;QI Xiao-li;ZHANG Li-ying(Department of Pathology,Daxing Teaching Hospital,Capital Medical University,Beijing 102600,China)

机构地区：[1]首都医科大学大兴教学医院病理科,北京102600

出　　处：《临床和实验医学杂志》2024年第11期1196-1199,共4页Journal of Clinical and Experimental Medicine

基　　金：北京市大兴区科技发展计划项目(编号:KT2015000140);北京市大兴区人民医院院级课题项目(编号:4201801204)。

摘　　要：目的 探讨乳腺微创旋切手术中肿瘤良恶性与临床病理特征的相关性,以减少旋切样本中出现恶性病例的可能性。方法 回顾性收集2016年1月至2023年12月首都医科大学大兴教学医院收治的855例乳腺旋切病例的临床病理资料,整理并分析肿瘤良恶性与患者年龄、肿瘤最大径、肿瘤单双侧情况及术前超声BI-Rads分级的相关性。结果 855例乳腺微创旋切样本中,良性病例826例(96.6%),恶性病例29例(3.4%)。在旋切病例中,年龄>45岁、肿瘤最大径>2 cm、双侧乳腺均发生肿瘤及术前超声BI-Rads分级高于4a级为发生乳腺恶性肿瘤的4个危险因素(P<0.05);当患者具有2个以上的上述危险因素时,发生恶性肿瘤的概率更高(P<0.05)。结论 选择乳腺微创旋切术前,建议对患者的年龄、肿瘤最大径、肿瘤单双侧情况及超声BI-Rads分级情况进行综合评估,具有2个以上危险因素的患者,在术前加做其他影像学检查或穿刺活检进一步明确肿物性质后再进行旋切术式选择,可使微创旋切术获得更精准的应用。Objective To investigate the correlation between benign tumors,malignant tumors,and clinicopathological features in minimally invasive breast rotation surgery,so as to reduce the possibility of malignant patients in breast rotation samples.Methods The clinicopathological data of 855 cases of breast spiral resection in Daxing Teaching Hospital,Capital Medical University from January 2016 to December 2023 were retrospectively collected,and the correlation between benign,malignant tumors and the age,maximum tumor diameter,unilateral and bilateral tumor conditions and preoperative ultrasound BI-Rads grade of patients were analyzed.Results Among the 855 samples of minimally invasive breast circumcision,there were 826 benign cases(96.6%)and 29 malignant cases(3.4%).In the cases of spiral resection,age>45 years old,maximum tumor diameter>2 cm,both breast tumors and preoperative ultrasound BI-Rads grades higher than 4a were the four risk factors for breast malignancy(P<0.05).When patients had more than 2 of the above risk factors,the possibility of malignant tumor was higher(P<0.05).Conclusion Before the selection of minimally invasive breast resection,it is recommended to conduct a comprehensive evaluation of the patient's age,maximum tumor diameter,unilateral and bilateral tumor conditions,and ultrasound BI-Rads grade.For patients with more than two risk factors,other imaging examinations or puncture biopsy should be performed before the selection of rotary resection to further clarify the nature of the tumor.It can make the application of minimally invasive surgery more precise.

关 键 词：乳腺肿瘤 危险因素 乳腺微创旋切术 相关性 

分 类 号：R737.9[医药卫生—肿瘤]