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作 者:苏飞 徐琳琳 王强[3] SU Fei;XU Linlin;WANG Qiang(Binzhou Medical University,Shandong,Yantai 264000,China;Customer Service Center,Jinan Stomatological Hospital,Shandong,Jinan 250001,China;Department of Special Diagnosis,Jinan Stomatological Hospital,Shandong,Jinan 250001,China)
机构地区:[1]滨州医学院,山东烟台264000 [2]济南市口腔医院客服中心,山东济南250001 [3]济南市口腔医院特诊科,山东济南250001
出 处:《中国医药科学》2024年第12期30-34,共5页China Medicine And Pharmacy
基 金:山东省济南市口腔医院院长助研基金面上项目(2022-02)。
摘 要:低强度脉冲超声(LIPUS)是一种安全且简单易行的非侵入性物理治疗方式,通过低强度、脉冲式的超声波刺激人体组织以产生生物学效应,现已广泛应用于加速多种组织的修复和再生。早期发现LIPUS在治疗骨折愈合方面显示出积极作用,随着对其生物学机制的探索,逐渐发现其对炎症的抑制及神经调节作用。现如今,其临床应用逐渐扩展至口腔颌面部骨组织的愈合。口腔种植修复为获得与天然牙功能、结构以及美观效果十分相近的修复疗效,种植体周围软硬组织的恢复重建则至关重要。研究发现超声刺激可对种植术后种植体周围组织产生生物学作用。本文综述LIPUS的作用机制及其对种植体周围组织的研究与应用进展,以期为其应用于临床种植修复提供理论依据。Low intensity pulsed ultrasound(LIPUS)is a safe,simple and easy non-invasive physical therapy method.It stimulates human tissues with low-intensity pulsed ultrasound to produce biological effects,and has been widely used to accelerate the repair and regeneration of various tissues.Early discovery of LIPUS showed positive effect in the treatment of fracture healing.With the exploration of its biological mechanism,it is gradually discovered that LIPUS could inhibit inflammation and regulate nerves.Nowadays,its clinical application is gradually extended to the healing of oral and maxillofacial bone tissue.In order to obtain the restoration effect which is very similar to the function,structure and aesthetic effect of natural teeth,it is very important to restore and reconstruct the soft and hard tissues around the implant.It is found that ultrasonic stimulation can have biological effects on the tissues around the implant after implantation operation.In this paper,the function mechanism of LIPUS and its research and application progress in peri-implant tissues are reviewed,so as to provide theoretical basis for its application in clinical implant restoration.
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