乳腺癌新辅助全身治疗后保留腋窝的研究进展  

Axilla-conserving therapy in breast cancer patients after neoadjuvant systemic therapy:a literature review

作　　者：邱子涵 王淑莲 Qiu Zihan;Wang Shulian(Department of Radiation Oncology,National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital,Chinese Academy of Medical Sciences and Peking Union Medical College,Beijing 100021,China)

机构地区：[1]国家癌症中心/国家肿瘤临床医学研究中心/中国医学科学院北京协和医学院肿瘤医院放疗科,北京100021

出　　处：《中华放射肿瘤学杂志》2024年第7期661-667,共7页Chinese Journal of Radiation Oncology

摘　　要：乳腺癌新辅助全身治疗的有效率提高,使患者的腋窝治疗朝着降低治疗强度、保留腋窝的方向发展。尤其对于新辅助治疗后腋窝淋巴结降期的患者,豁免腋窝淋巴结清扫成为可能。但腋窝放疗能否取代腋窝淋巴结清扫仍有待进一步研究。另外,如何对腋窝转移淋巴结能达到病理完全缓解的患者进行预测,以挑选出能够豁免腋窝手术的人群也是临床关注的焦点。本文对乳腺癌新辅助全身治疗后保留腋窝的研究进展进行综述。With the development of effective neoadjuvant systemic therapy for breast cancer,there is a trend towards reducing the surgical treatment intensity and conserving the axilla.It is possible to omit axillary lymph node dissection for patients with axillary downstaging after neoadjuvant systemic therapy.However,whether axillary radiotherapy can replace axillary lymph node dissection remains to be further studied.The complete omission of axillary surgery is also the focus of clinical research for patients who can be predicted to achieve axillary pathological complete response.In this article,we provide an overview of recent research progress in axilla-conserving therapy for breast cancer patients after neoadjuvant systemic therapy.

关 键 词：乳腺肿瘤 新辅助全身治疗 前哨淋巴结活组织检查 

分 类 号：R737.9[医药卫生—肿瘤] R730.5[医药卫生—临床医学]