结直肠癌肝转移的非根治性切除手术治疗策略  

Treatment strategy of non-radical surgical resection for colorectal cancer liver metastases

作　　者：张瑞 陈进宏 ZHANG Rui;CHEN Jinhong(Center of Hepatobiliary Surgery,Department of General Surgery,Huashan Hospital,Fudan University,Shanghai 200040,China)

机构地区：[1]复旦大学附属华山医院普外科肝胆外科中心,上海200040

出　　处：《临床肝胆病杂志》2024年第7期1295-1300,共6页Journal of Clinical Hepatology

基　　金：国家自然科学基金(82272836);上海市“科技创新行动计划”优秀学术带头人计划项目(22XD1400300)。

摘　　要：有效治疗结直肠癌肝转移是提高结直肠癌患者生存率和生活质量的关键。随着系统性化疗的应用,结直肠癌肝转移患者的转化率和手术切除率越来越高。非根治性切除手术是肿瘤外科的手术策略之一。本文将主要针对结直肠癌肝转移初始不可切除患者,包括存在肝外转移、肝转移瘤R1切除以及肝转移瘤分步手术和减瘤手术等,阐述非根治性切除手术在结直肠癌肝转移治疗中的应用。Effective treatment of colorectal cancer liver metastases is crucial for improving the survival rate and quality of life of patients with colorectal cancer.With the application of systemic chemotherapy,there have been increases in the conversion rate and surgical resection rate of patients with colorectal cancer liver metastases.Non-radical resection is one of the surgical strategies in tumor surgery.This article reviews the treatment of patients with initially unresectable colorectal cancer liver metastases,including extrahepatic metastasis,R1 resection of liver metastases,staged surgery for liver metastases,and debulking surgery,as well as the application of non-radical resection in the treatment of colorectal cancer liver metastases.

关 键 词：结直肠肿瘤 肿瘤转移 肝 治疗学 

分 类 号：R735.34[医药卫生—肿瘤]