Caudal hematopoietic tissue supports definitive erythrocytes via epoa and is dispensable for definitive neutrophils  

作　　者：Zhujuan Huang Yongtai Xu Zhongkai Qiu Yunyun Jiang Jiaye Wu Qing Lin Sicong He Jianan Y.Qu Jiahao Chen Jin Xu 

机构地区：[1]Innovation Centre of Ministry of Education for Development and Diseases,School of Medicine,South China University of Technology,Guangzhou,Guangdong 510006,China [2]Department of Biology,School of Life Sciences,Southern University of Science and Technology,Shenzhen,Guangdong 518055,China [3]Department of Electronic and Computer Engineering,The Hong Kong University of Science and Technology,Kowloon,Hongkong 999077,China

出　　处：《Journal of Genetics and Genomics》2024年第6期669-672,共4页遗传学报（英文版）

基　　金：supported by the National Key Research and Development Program of China(2018YFA0800200);the National Natural Science Foundation of China/ResearchGrantsCouncilJointResearchScheme(31961160726);the National Natural Science Foundation of China(32170827 and 32370886);the Research Grants Council of Hong Kong(RGC/NFSC N_HKUST603/19).

摘　　要：The blood system originates from hematopoietic stem cells(HSCs),capable of self-renewal and differentiation,generating diverse blood cell types(Eaves,2015;Lucas,2021).The concept of the hematopoietic niche was first proposed in 1978(Schofield,1978),which is crucial for maintaining hematopoietic balance.The following studies,particularly in mammals,have utilized targeted genetic manipulation to identify and define these niches.

关 键 词：HEMATOPOIETIC MANIPULATION utilized 

分 类 号：R392[医药卫生—免疫学]