种植体表面特性对细菌黏附的影响研究进展  

Research progress on the effect of implant surface characteristics on bacterial adhesion

作　　者：冯丹峰 黎红[1,2] FENG Danfeng;LI Hong(School of Stomatology,Zhejiang Chinese Medical University,Hangzhou 310053,China;Department of Stomatology,Xiaoshan Branch of Hangzhou Stomatology Hospital,Hangzhou 311200,China)

机构地区：[1]浙江中医药大学口腔医学院,浙江杭州310053 [2]杭州口腔医院萧山分院口腔科,浙江杭州311200

出　　处：《空军军医大学学报》2024年第7期838-840,F0003,共4页Journal of Air Force Medical University

基　　金：浙江省卫生健康科技计划项目(2022KY264)。

摘　　要：种植体周围细菌在种植体表面的早期黏附是种植体周围炎的重要致病因素之一,不同的表面处理方式对细菌的黏附产生着不同的影响。本文通过分析生物膜的形成机制和影响因素,探讨了光滑钛、大颗粒喷砂酸蚀表面和阳极氧化等不同表面特性对细菌黏附和生物膜形成的影响,同时介绍了物理改性和生物修饰技术对增强种植体抗菌性能的影响,探索各种表面处理技术在抑制这些生物膜形成方面的有效性,为优化种植体设计和提高其临床应用安全性提供科学依据。Bacterial adhesion to the surface of implants in the early stage is one of the important pathogenic factors in peri-implantitis.The impact of different surface treatments on bacterial adhesion varies significantly.This paper analyzes the formation mechanisms and influencing factors of biofilms,explores the effect of different surface characteristics such as smooth titanium,sandblasted,large-grit,acid-etched surfaces,and anodic oxidation on bacterial adhesion and biofilm formation.Additionally,the paper introduces the influence of physical and biological surface modification techniques on enhancing antibacterial performance of implants.By exploring the efficacy of various surface treatment techniques in inhibiting the formation of these biofilms,this paper provides a scientific basis for optimizing implant design and enhancing the safety of clinical application.

关 键 词：种植体 细菌黏附 生物膜 表面特性 表面修饰 

分 类 号：R783.6[医药卫生—口腔医学]