Rescuing the Golgi from heat damages by ATG8:restoration rather than clean-up  

作　　者：Anni Luo Jian-Xiang Liu 

机构地区：[1]State Key Laboratory of Plant Physiology and Biochemistry,College of Life Sciences,Zhejiang University,Hangzhou 310027,China

出　　处：《Stress Biology》2023年第1期219-221,共3页逆境生物学（英文）

基　　金：financially supported by grants from the State Key Project of Research and Development Plan(2021YFF1000404,2022YFF1001603).

摘　　要：High temperature stress poses significant adverse effects on crop yield and quality.Yet the molecular mechanisms underlying heat stress tolerance in plants/crops,especially regarding the organellar remodeling and homeostasis,are largely unknown.In a recent study,Zhou et al.reported that autophagy-related 8(ATG8),a famous regulator involved in autophagy,plays a new role in Golgi restoration upon heat stress.Golgi apparatus is vacuolated following short-term acute heat stress,and ATG8 is translocated to the dilated Golgi membrane and interacts with CLATHRIN LIGHT CHAIN 2(CLC2)to facilitate Golgi restoration,which is dependent on the ATG conjugation system,but not of the upstream autophagic initiators.These exciting findings broaden the fundamental role of ATG8,and elucidate the organelle-level restoration mechanism of Golgi upon heat stress in plants.

关 键 词：ATG8 AUTOPHAGY CLC2 ER Golgi restoration Heat stress 

分 类 号：Q945.78[生物学—植物学]