Hybrid argon plasma coagulation for the treatment of Barrett’s esophagus:A prospective,multicenter study  

作　　者：Dong Wang Yan Chen Feng Ji Jian-Wei Hu Ping-Hong Zhou Shu-Chang Xu Ying Chen Li-Ping Ye Guo-Liang Ye Rui Li Zhao-Shen Li 

机构地区：[1]Department of Gastroenterology,Shanghai Ninth People's Hospital Affiliated to Shanghai Jiaotong University School of Medicine,Shanghai 200011,China [2]Department of Gastroenterology,Changhai Hospital,Shanghai 200438,China [3]Department of Gastroenterology,The First Affiliated Hospital Zhejiang University School of Medicine,Hangzhou 311399,Zhejiang Province,China [4]Endoscopy Center,Zhongshan Hospital,Fudan University,Shanghai 200032,China [5]Endoscopy Center,Tongji Hospital of Tongji University,Shanghai 200092,China [6]Department of Gastroenterology,Taizhou Hospital of Zhejiang Province,Taizhou 318001,Zhejiang Province,China [7]Department of Gastroenterology,The Affiliated Hospital of Medicine School,Ningbo University,Ningbo 315021,Zhejiang Province,China [8]Department of Gastroenterology,The First Affiliated Hospital of Soochow University,Suzhou 215006,Jiangsu Province,China

出　　处：《World Journal of Clinical Cases》2024年第19期3866-3872,共7页世界临床病例杂志

摘　　要：BACKGROUND The incidence of Barrett’s esophagus(BE)in China is lower compared to the Western populations.Hence,studies conducted in the Chinese population has been limited.The current treatment options available for BE treatment includes argon plasma coagulation(APC),radiofrequency ablation and cryoablation,all with varying degrees of success.AIM To determine the efficacy and safety of HybridAPC in the treatment of BE.METHODS The study cohort consisted of patients with BE who underwent HybridAPC ablation treatment.These procedures were performed by seven endoscopists from different tertiary hospitals.The duration of the procedure,curative rate,complications and recurrent rate by 1-year follow-up were recorded.RESULTS Eighty individuals were enrolled for treatment from July 2017 to June 2020,comprising of 39 males and 41 females with a median age of 54 years(range,30 to 83 years).The technical success rate of HybridAPC was 100%and the overall curative rate was 98.15%.No severe complications occurred during the operation.BE cases were classified as short-segment BE and long-segment BE.Patients with short-segment BE were all considered cured without complications.Thirty-six patients completed the one-year follow-up without recurrence.Twenty-four percent had mild dysplasia which were all resolved with one post-procedural treatment.The mean duration of the procedure was 10.94±6.52 min.CONCLUSION Treatment of BE with HybridAPC was found to be a simple and quick procedure that is safe and effective during the short-term follow-up,especially in cases of short-segment BE.This technique could be considered as a feasible alternative ablation therapy for BE.

关 键 词：Barrett’s esophagus Hybrid argon plasma coagulation Ablation treatment Prospective study Multicenter study 

分 类 号：R571[医药卫生—消化系统]