Influence of a diet meal plan on pepsinogen I and II,gastrin-17,and nutritional status in gastric ulcer patients  

作　　者：Wei-Wei Zhang Xiao-Fei Wang Hai-Yan Yu Ling-Fang Wang 

机构地区：[1]Department of Gastroenterology,Lujiang County Hospital of Traditional Chinese Medicine,Hefei 231500,Anhui Province,China [2]Department of Anorectal Surgery,Lujiang County Hospital of Traditional Chinese Medicine,Hefei 231500,Anhui Province,China

出　　处：《World Journal of Clinical Cases》2024年第21期4574-4581,共8页世界临床病例杂志

基　　金：the Ethic Committee of Lujiang County Hospital of Traditional Chinese Medicine.

摘　　要：BACKGROUND Gastric ulcers(GUs)have a high risk of clinical morbidity and recurrence,and further exploration is needed for the prevention,diagnosis,and treatment of the disease.AIM To investigated the effects of a diet plan on pepsinogen(PG)I,PG II,gastrin-17(G-17)levels and nutritional status in patients with GUs.METHODS A total of 100 patients with GUs treated between May 2022 and May 2023 were enrolled,with 47 patients in the control group receiving routine nursing and 53 patients in the experimental group receiving dietary nursing intervention based on a diet plan.The study compared the two groups in terms of nursing efficacy,adverse events(vomiting,acid reflux,and celialgia),time to symptom improvement(burning sensation,acid reflux,and celialgia),gastric function(PG I,PG II,and G-17 levels),and nutritional status[prealbumin(PA)and albumin(ALB)levels].RESULTS The experimental group showed a markedly higher total effective rate of nursing,a significantly lower incidence of adverse events,and a shorter time to symptom improvement than the control group.Additionally,the experimental group’s post-intervention PG I,PG II,and G-17 levels were significantly lower than preintervention or control group levels,whereas PA and ALB levels were significantly higher.CONCLUSION The diet plan significantly reduced PG I,PG II,and G-17 levels in patients with GUs and significantly improved their nutritional status.

关 键 词：Diet plan Dietary care Gastric ulcers Plan on pepsinogen I Plan on pepsinogen II GASTRIN-17 

分 类 号：R573.1[医药卫生—消化系统] R573.2[医药卫生—内科学]