Hepatoid adenocarcinoma of the lung:A case report  

作　　者：Yi-Jun Mo Li-Na Lin Jing-Li Tao Tao Zhang Jian-Hua Zhang 

机构地区：[1]Department of Thoracic Surgery,Shenzhen Hospital,Southern Medical University,Shenzhen 518104,Guangdong Province,China [2]School of Nursing,Guangzhou Xinhua University,Guangzhou 510520,Guangdong Province,China [3]Department of Pathology,Shenzhen Hospital,Southern Medical University,Shenzhen 518104,Guangdong Province,China

出　　处：《World Journal of Clinical Cases》2024年第21期4813-4819,共7页世界临床病例杂志

基　　金：Research Fund of Basic Research Project of Shenzhen(Natural Science Foundation of Shenzhen),No.JCYJ20230807142205010.

摘　　要：BACKGROUND Hepatoid adenocarcinoma of the lung(HAL)is a rare type of non-small cell lung cancer(NSCLC),histologically similar to hepatocellular carcinoma.HAL has high malignancy and poor prognosis,and a better treatment plan needs further study.CASE SUMMARY In order to deeply understand the occurrence and development of HAL,here we report a case of HAL with extensive metastasis of alpha fetoprotein negative KRAS A146T mutation.The patient refused chemotherapy and received one course of treatment(immune checkpoint inhibitors),and died three months later due to progressive disease.CONCLUSION HAL is a special type of NSCLC.The surgical treatment of HAL in the limited stage can achieve long-term survival,but most of them were in the advanced stage when they were found,and the prognosis was poor,which requires multidisciplinary comprehensive treatment.

关 键 词：Hepatoid adenocarcinoma Histopathological characteristics Non-small cell lung cancer Hepatoid adenocarcinoma of the lung Case report 

分 类 号：R735[医药卫生—肿瘤]