Application of dezocine patient-controlled epidural analgesia in postoperative analgesia in patients with total myomectomy  

作　　者：Feng-Feng Ning Ting-Ting Yao Xiao-Xia Wang 

机构地区：[1]Department of Anesthesiology,Gansu Provincial Maternity and Child-care Hospital,Lanzhou 730050,Gansu Province,China [2]Department of Gynecology,Gansu Provincial Maternity and Child-Care Hospital,Lanzhou 730050,Gansu Province,China

出　　处：《World Journal of Clinical Cases》2024年第20期4265-4271,共7页世界临床病例杂志

基　　金：Natural Science Foundation of Gansu Provincial Science and Technology Department(Basic Research Program),No.23JRRA1385.

摘　　要：BACKGROUND Uterine fibroids are common benign gynecological conditions.Patients who experience excessive menstruation,anemia,and pressure symptoms should be administered medication,and severe cases require a total hysterectomy.This procedure is invasive and causes severe postoperative pain,which can affect the patient’s postoperative sleep quality and,thus,the recovery process.AIM To evaluate use of dezocine in patient-controlled epidural analgesia(PCEA)for postoperative pain management in patients undergoing total myomectomy.METHODS We selected 100 patients undergoing total abdominal hysterectomy for uterine fibroids and randomized them into two groups:A control group receiving 0.2%ropivacaine plus 0.06 mg/mL of morphine and an observation group receiving 0.2%ropivacaine plus 0.3 mg/mL of diazoxide in their PCEA.Outcomes assessed included pain levels,sedation,recovery indices,PCEA usage,stress factors,and sleep quality.RESULTS The observation group showed lower visual analog scale scores,shorter postoperative recovery indices,fewer mean PCEA compressions,lower cortisol and blood glucose levels,and better polysomnographic parameters compared to the control group(P<0.05).The cumulative incidence of adverse reactions was lower in the observation group than in the control group(P<0.05).CONCLUSION Dezocine PCEA can effectively control the pain associated with total myomectomy,reduce the negative impact of stress factors,and have less impact on patients’sleep,consequently resulting in fewer adverse effects.

关 键 词：DIAZOXIDE Patient-controlled epidural analgesia Total hysterectomy Sleep impacts Adverse effects 

分 类 号：R713[医药卫生—妇产科学]