云南高校图书馆联盟文献共享服务平台- DIAZOXIDE

DIAZOXIDE: 作品数：19被引量：33H指数：4; 导出分析报告; 相关领域：医药卫生更多>>; 相关作者：宋治远仝识非钟理胡红玲赵建平更多>>; 相关机构：第三军医大学西南医院华中科技大学第三军医大学附属西南医院重庆医科大学更多>>; 相关期刊：《介入放射学杂志》《Chinese Medical Journal》《外科研究与新技术（中英文）》《中国心脏起搏与心电生理杂志》更多>>; 相关基金：国家自然科学基金国家教育部博士点基金国家科技支撑计划更多>>

Diazoxide toxicity in congenital hyperinsulinism:A case report: 《World Journal of Clinical Pediatrics》2024年第4期102-108,共7页Roberta Pajno Camilla Visconti Carmen Bucolo Maria Pia Guarneri Paolo Del Barba Paolo Silvani Marco Gregnanin Graziano Barera; BACKGROUND Diazoxide is the sole approved drug for congenital hyperinsulinism;however,diuretic administration and vigilant monitoring are crucial to prevent and promptly identify potentially life-threatening adverse e...; 关键词：DIAZOXIDE HYPOGLYCEMIA Congenital hyperinsulinism Side effect Case report

Application of dezocine patient-controlled epidural analgesia in postoperative analgesia in patients with total myomectomy: 《World Journal of Clinical Cases》2024年第20期4265-4271,共7页Feng-Feng Ning Ting-Ting Yao Xiao-Xia Wang; Natural Science Foundation of Gansu Provincial Science and Technology Department(Basic Research Program),No.23JRRA1385.; BACKGROUND Uterine fibroids are common benign gynecological conditions.Patients who experience excessive menstruation,anemia,and pressure symptoms should be administered medication,and severe cases require a total hys...; 关键词：DIAZOXIDE Patient-controlled epidural analgesia Total hysterectomy Sleep impacts Adverse effects

Efficacy and safety of octreotide treatment for diazoxide-unresponsive congenital hyperinsulinism in China被引量：1: 《Pediatric Investigation》2020年第1期29-36,共8页Bingyan Cao Di Wu Chang Su Jiajia Chen Xuejun Liang Min Liu Wenjing Li Xiaoqiao Li Chunxiu Gong; The study was funded by National Key Research and Development Program of China(2016YFC1305304);Beijing Children's Hospital Young Investigator Program(No.BCHYIPA-2016-06);Beijing Municipal Administration of Hospital Clinical Medicine Development of Special Funding Support(No.ZYLX201821).; Importance: Octreotide is an off-label medicine for congenital hyperinsulinism (CHI), but is currently widely used for treatment of patients with CHI. Thus far, variable efficacy and adverse effects have been reported...; 关键词：OCTREOTIDE Congenital hyperinsulinism EFFICACY Safety

Beneficial effects of adenosine triphosphate-sensitive K^+ channel opener on liver ischemia/reperfusion injury被引量：3: 《World Journal of Gastroenterology》2014年第41期15319-15326,共8页Mateus Antunes Nogueira Ana Maria Mendona Coelho Sandra Nassa Sampietre Rosely Antunes Patzina Fabiano Pinheiro da Silva Luiz Augusto Carneiro D'Albuquerque Marcel Cerqueira Cesar Machado; Supported by Fundao de Amparoà Pesquisa do Estado de So Paulo,No.2010/19078-1; AIM: To investigate the effect of diazoxide administration on liver ischemia/reperfusion injury.; 关键词：Liver ischemia/reperfusion DIAZOXIDE K⁺ channel opener Mitochondrial ATP-sensitive potassium channel Liver mitochondria

Diazoxide preconditioning antagonizes cytotoxicity induced by epileptic seizures: 《Neural Regeneration Research》2013年第11期1000-1006,共7页Qingxi Fu Zhiqing Sun Jinling Zhang Naiyong Gao Faying Qi Fengyuan Che Guozhao Ma; supported by the Technology Development Plan of Linyi City, No. 201113002; Diazoxide, an activator of mitochondrial ATP-sensitive potassium channels, can protect neurons and astrocytes against oxidative stress and apoptosis. In this study, we established a cellular mode of epilepsy by cultur...; 关键词：neural regeneration ATP-sensitive potassium channel activator of mitochondrial ATP-sensitivepotassium channel epilepsy DIAZOXIDE inwardly recti^ing potassium channel subunit hippocampal neuron CYTOTOXICITY neuroprotection grants-supported paper NEUROREGENERATION

Diazoxide attenuates ischemia/reperfusion injuryvia upregulation of heme oxygenase-1 after liver transplantation in rats被引量：6: 《World Journal of Gastroenterology》2012年第15期1765-1772,共8页Zhong Zeng Han-Fei Huang Fei He Lin-Xi Wu Jie Lin Ming-Qing Chen; Supported by Social Development Projects of Yunnan Province,No.2008CA026; AIM:To evaluate the effects of diazoxide on ischemia/reperfusion(I/R)-injured hepatocytes and further elucidate its underlying mechanisms.METHODS:Male Sprague-Dawley rats were randomized(8 for donor and recipient per ...; 关键词：Ischemia/reperfusion injury DIAZOXIDE Heme oxygenase-1 Liver transplantation RAT

Neuroprotective effects of a mitochondrial K^+-ATP channel opener (diazoxide) are mediated by Bcl-2 expression upregulation被引量：2: 《Neural Regeneration Research》2011年第12期956-960,共5页Majid Katebi Mansooreh Soleimani Mehdi Mehdizadeh; Mitochondrial K＋-ATP （mito-KATP） channels play an important role in cellular function and survival following ischemic stress. The present results revealed that intervention with diazoxide, a mito-KATP channel opene...; 关键词：K-ATP channel BCL-2 cerebral ischemia reperfusion injury DIAZOXIDE

Current understanding of KATP channels in neonatal diseases： focus on insulin secretion disorders被引量：4: 《Acta Pharmacologica Sinica》2011年第6期765-780,共16页Yi QUAN Andrew BARSZCZYK Zhong-ping FENG Hong-shuo SUN; ATP-sensitive potassium （KATP） channels are ceil metabolic sensors that couple cell metabolic status to electric activity, thus regulat- ing many cellular functions. In pancreatic beta cells, KATp channels modulate ...; 关键词：ATP-sensitive potassium （KATp） channels CHANNELOPATHY neonatal diabetes congenital hyperinsulinism glucose homeostasis DIAZOXIDE SULFONYLUREAS

Diazoxide对缺氧大鼠肺动脉平滑肌细胞内氧自由基的变化及细胞增殖的作用被引量：8: 《中国病理生理杂志》2007年第10期2002-2006,共5页胡红玲汪涛张珍祥赵建平徐永健; 国家自然科学基金资助项目(No.30370623); 目的:研究线粒体膜上ATP敏感钾通道(MitoKATP)开放剂diazoxide和线粒体膜电位(ΔΨm)在缺氧导致的大鼠肺动脉平滑肌细胞内氧自由基的变化及细胞增殖/凋亡失衡中的作用,探索缺氧性肺动脉重建和肺动脉高压形成的发生机制。方法:取大鼠正...; 关键词：肺动脉平滑肌细胞缺氧线粒体膜电位线粒体ATP敏感性钾通道活性氧

Differentially expressed phosphoproteins in diazoxide-pretreated ventricular myocytes by two-dimensional electrophoresis and mass spectrometry in vitro: 《Journal of Medical Colleges of PLA(China)》2006年第3期143-147,共5页李洪肖颖彬高玉琪杨天德; Supported by the National Natural Science Foundation of China (No. 30200089 and No. 30500211); Objectives To analyze and identify differentially expressed phosphoproteins associated with mitochondrial KATP channel opening. Methods： Adult rat ventricular myocytes were isolated, cultured, and identified, and pre...; 关键词：PRECONDITIONING mitochondrial KATP channel two-dimensional gel electrophoresis ventricular myocytes DIAZOXIDE

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