OCTREOTIDE

作品数:140被引量:496H指数:12
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相关领域:医药卫生更多>>
相关作者:范我孙俊杰朱然章斌许玉杰更多>>
相关机构:苏州大学第四军医大学西京医院中国原子能科学研究院青岛大学更多>>
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相关基金:国家自然科学基金国家重点基础研究发展计划江苏省社会发展科技计划广东省医学科学技术研究基金更多>>
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Structural insights into somatostatin receptor 5 bound with cyclic peptides
《Acta Pharmacologica Sinica》2024年第11期2432-2440,共9页Ying-ge Li Xian-yu Meng Xiru Yang Sheng-long Ling Pan Shi Chang-lin Tian Fan Yang 
supported by“USTC Research Funds of the Double First-Class Initiative”(YD9990002027 to FY,YD9100002021 to PS);the National Natural Science Foundation of China(22207100 to FY,22277114,31971152 to PS,21825703 to CLT,22307113 to SLL);the National Key Research&Development Project,Ministry of Science and Technology the China(2022YFC3400500 to CLT);Postdoctoral Science Foundation(2022M713054 to FY);the Strategic Priority Research Program of Chinese Academy of Sciences(XDB37000000 to CLT);Anhui Provincial Natural Science Foundation(2108085J16 to PS);And the National Key R&D Program of China(2021YFA1200104 to SLL);supported by“the Fundamental Research Funds for the Central Universities”.
Somatostatin receptor 5(SSTR5)is highly expressed in ACTH-secreting pituitary adenomas and is an important drug target for the treatment of Cushing’s disease.Two cyclic SST analog peptides(pasireotide and octreotide)...
关键词:G protein-coupled receptors Somatostatin receptor 5 PASIREOTIDE OCTREOTIDE CRYO-EM 
On implications of somatostatin in diabetic retinopathy
《Neural Regeneration Research》2024年第9期1984-1990,共7页Yanhong Fang Qionghua Wang Youjian Li Li Zeng Jian Liu Kepeng Ou 
supported by the Natural Science Foundation of Chongqing of China,Nos.cstc2020jcyj-msxmX0698(to YF),cstc2021jcyjbshX0147(to KO);a grant from Chongqing Jiangjin District Bureau of Science and Technology,No.Y2022017(to YF).
Somatostatin,a naturally produced neuroprotective peptide,depresses excitatory neurotransmission and exerts anti-proliferative and anti-inflammatory effects on the retina.In this review,we summarize the progress of so...
关键词:diabetes retinopathy EXCITOTOXICITY growth hormone insulin like growth factor irisin NEURODEGENERATION NEUROINFLAMMATION neuroprotection neurovascular unit OCTREOTIDE oxidative stress SOMATOSTATIN 
^(18)F-AlF-NOTA-octreotide/^(18)F-PSMA-1007 PET/CT联合显像诊断前列腺腺癌伴神经内分泌癌1例
《中华核医学与分子影像杂志》2024年第1期43-45,共3页田蓉蓉 赵铭 薄云峰 郝海龙 邢军 周洁 
山西省科技厅重点研发计划项目(201903D321187)。
患者男, 62岁, 1年前经盆腔MRI、骨显像(图1)及前列腺12针穿刺活组织检查(简称活检)确诊为前列腺癌(腺癌, Gleason评分:5+5=10分), 双侧精囊腺受侵, 双侧髂血管周多发淋巴结转移, 多发骨转移(包括胸骨、多发肋骨、椎体、骨盆、双侧肩关...
关键词:股骨上段 GLEASON评分 神经内分泌癌 前列腺腺癌 定期复查 骨显像 局部骨质 癌胚抗原 
State-of-the-art management for challenging complications in head and neck surgery
《Plastic and Aesthetic Research》2023年第1期18-27,共10页Kiran Ganga Caitlin McMullen 
Head and neck surgical complications can result in significant morbidity for patients.Innovations over the past few years have shown promise in mitigating these effects.Specifically,new medications,bioactive agents,an...
关键词:Chylous fistula venous thrombosis nerve injury microvascular free flap OCTREOTIDE FISTULA 
Successful Treatment with <sup>177</sup>Lutetium-Dotatate and Maintenance Octreotide in a Patient with Esthesioneuroblastoma with Central Nervous System Invasion: Case Report and Review of the Literature
《International Journal of Otolaryngology and Head & Neck Surgery》2023年第1期8-20,共13页Gabriela Dombrowski Laura Fernandes Ferreira Dalcin Francisco Assis Coelho Patricia Massucheto Ledesma Daniel Herchenhorn 
This article presents a case of a patient with relapsed esthesioneuroblastoma (ENB), an aggressive rare tumor that arises from the specialized sensory epithelial olfactory cells in the skull base area, which was initi...
关键词:ESTHESIONEUROBLASTOMA Olfactory Neuroblastoma Peptide Receptor Radionuclide Therapy PRRT 177Lutetium 
Role of octreotide in small bowel bleeding被引量:1
《World Journal of Clinical Cases》2022年第26期9192-9206,共15页Anwar Khedr Esraa Elaraby Mahmoud Noura Attallah Mikael Mir Sydney Boike Ibtisam Rauf Abbas B Jama Hisham Mushtaq Salim Surani Syed A Khan 
Gastrointestinal bleeding accounts for a drastic negative impact on the quality of the patients’lives as it requires multiple diagnostic and therapeutic interventions to identify the source of the bleeding.Small bowe...
关键词:OCTREOTIDE Small bowel HEMORRHAGE ANGIODYSPLASIA Vascular malformations Hereditary hemorrhagic telangiectasia 
Vasoactive intestinal peptide secreting tumour:An overview被引量:1
《World Journal of Gastrointestinal Oncology》2022年第4期808-819,共12页Esther Una Cidon 
Vasoactive intestinal peptide(VIP)secreting tumour(VIPoma)is a rare functional neuroendocrine tumour that typically arises from pancreatic islet cells.These present as sporadic,solitary pancreatic neoplasias with an e...
关键词:VIPOMA OCTREOTIDE Secretory diarrhoea Multiple endocrine neoplasia Vasoactive intestinal peptide Vermer-Morrison syndrome 
Evaluation of the Efficacy of Ulinastatin Combined with Octreotide in the Treatment of Senile Acute Severe Pancreatitis
《外文科技期刊数据库(文摘版)医药卫生》2021年第12期113-114,共4页MIAO Yuhao 
Objective: to explore the clinical effect of ulinastatin combined with octreopeptide in elderly patients with severe acute pancreatitis. Methods: in this study, with the approval of the hospital ethics committee, 90 p...
关键词:senile acute severe pancreatitis COMPLICATIONS therapeutic effect ULINASTATIN 
Octreotide-induced acute life-threatening gallstones after vicarious contrast medium excretion:A case report被引量:2
《World Journal of Clinical Cases》2021年第25期7484-7489,共6页Zong-Hong Han Zhong-Ming He Wen-Hua Chen Cao-Ye Wang Qi Wang 
the Changzhou Commission of Health,No.WZ201904.
BACKGROUND Octreotide is widely used for the treatment of acromegaly,neuroendocrine tumors,and secretory diarrhea.However,long-term octreotide treatment can increase the incidence of gallstones.Vicarious contrast medi...
关键词:OCTREOTIDE GALLSTONES Contrast medium Case report 
^(18)F-AlF-NOTA-octreotide联合^(18)F-FDG PET/CT显像用于神经内分泌瘤被引量:7
《中国医学影像技术》2021年第5期663-668,共6页陈博 冯洪波 宫晓艳 杜雪梅 
目的观察^(18)F-AlF-NOTA-octreotide(^(18)F-OCT)联合^(18)F-FDG PET/CT显像用于神经内分泌瘤(NET)的临床价值。方法回顾性分析21例同期接受^(18)F-OCT和^(18)F-FDG PET/CT显像并经病理学证实的NET患者,其中7例已接受原发瘤根治性切除...
关键词:神经内分泌瘤 正电子发射断层显像 体层摄影术 X线计算机 ^(18)F氟脱氧葡萄糖 ^(18)F-AlF-NOTA-octreotide 
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