Role of octreotide in small bowel bleeding  

作　　者：Anwar Khedr Esraa Elaraby Mahmoud Noura Attallah Mikael Mir Sydney Boike Ibtisam Rauf Abbas B Jama Hisham Mushtaq Salim Surani Syed A Khan 

机构地区：[1]Department of Internal Medicine,BronxCare Health System,Bronx,NY 10457,United States [2]Department of Medicine,University of Sharjah,Sharjah 27272,United Arab Emirates [3]Critical Care Medicine,Mayo Clinic Health System,Mankato,MN 56001,United States [4]Department of Medicine,University of Minnesota,Minneapolis,MN 55455,United States [5]Department of Medicine,St.George School of Medicine,Grenada,West Indies [6]Department of Medicine,Texas A&M University Health Science Center,Bryan,TX 77807,United States

出　　处：《World Journal of Clinical Cases》2022年第26期9192-9206,共15页世界临床病例杂志

摘　　要：Gastrointestinal bleeding accounts for a drastic negative impact on the quality of the patients’lives as it requires multiple diagnostic and therapeutic interventions to identify the source of the bleeding.Small bowel bleeding is the least common cause of gastrointestinal bleeding.However,it is responsible for the majority of complaints from patients with persisting or recurring bleeding where the primary source of bleeding cannot be identified despite investigation.A somatostatin analog known as octreotide is among the medical treatment modalities currently used to manage small bowel bleeding.This medication helps control symptoms of gastrointestinal bleeding by augmenting platelet aggregation,decreasing splanchnic blood flow,and antagonizing angiogenesis.In this review article,we will highlight the clinical efficacy of octreotide in small bowel bleeding and its subsequent effect on morbidity and mortality.

关 键 词：OCTREOTIDE Small bowel HEMORRHAGE ANGIODYSPLASIA Vascular malformations Hereditary hemorrhagic telangiectasia 

分 类 号：R574.5[医药卫生—消化系统]