Octreotide-induced acute life-threatening gallstones after vicarious contrast medium excretion:A case report  

作　　者：Zong-Hong Han Zhong-Ming He Wen-Hua Chen Cao-Ye Wang Qi Wang 

机构地区：[1]Department of Interventional Radiology,The First People’s Hospital of Changzhou,Changzhou 213003,Jiangsu Province,China

出　　处：《World Journal of Clinical Cases》2021年第25期7484-7489,共6页世界临床病例杂志

基　　金：the Changzhou Commission of Health,No.WZ201904.

摘　　要：BACKGROUND Octreotide is widely used for the treatment of acromegaly,neuroendocrine tumors,and secretory diarrhea.However,long-term octreotide treatment can increase the incidence of gallstones.Vicarious contrast medium excretion(VCME)through the hepatobiliary system is well known.However,few studies have reported octreotide-induced acute gallstones following VCME.CASE SUMMARY A 69-year-old man presented with left lower back pain and hematuria caused by a fall.The patient had a history of polycystic kidney disease.VCME occurred following renal artery embolization for a ruptured polycystic kidney.After 5 d of treatment with octreotide,the patient developed acute gallstones and intrahepatic cholestasis which further induced pancreatitis and cholangitis.He was discharged after hemodialysis,antibiotics,and supportive treatments.CONCLUSION For patients with a high-risk of VCME,octreotide should be cautiously administered and carefully monitored.

关 键 词：OCTREOTIDE GALLSTONES Contrast medium Case report 

分 类 号：R575.62[医药卫生—消化系统]