Non-surgical treatment of diabetic foot ulcers on the dorsum of the foot with polydeoxyribonucleotide injection:Two case reports  

作　　者：Yooseok Ha Jeong-Hee Kim Jiyoung Kim Hyeokjae Kwon 

机构地区：[1]Department of Plastic and Reconstructive Surgery,Chungnam National University Hospital,Daejeon 35015,South Korea [2]College of Nursing,Woosuk University,Wanju-gun 55338,South Korea

出　　处：《World Journal of Clinical Cases》2024年第20期4446-4451,共6页世界临床病例杂志

摘　　要：BACKGROUND Diabetic foot ulcers are caused by a variety of factors,including peripheral neuropathy,peripheral arterial disease,impaired wound healing mechanisms,and repetitive trauma.Patients with diabetic foot ulcer on the dorsum of the foot are often treated surgically.However,the right non-surgical therapy must be chosen if surgical choices are contraindicated or if the patient prefers conservative treatment over surgery.CASE SUMMARY The purpose of this case report is to highlight the efficacy of polydeoxyribonucleotide(PDRN)injection as a non-surgical treatment option for diabetic foot ulcers on the dorsum of the foot,particularly in patients who choose against surgical intervention.This case report presents two cases of diabetic foot ulcers located on the dorsum of the foot that were successfully treated with PDRN injection as a non-surgical intervention.CONCLUSION If the patient declines surgery for diabetic ulcers with Wagner grade II or below,PDRN injection can be effective if necrotic tissue is removed and the wound bed kept clean.

关 键 词：Diabetic foot Wound healing Regenerative medicine POLYDEOXYRIBONUCLEOTIDES Case report 

分 类 号：R782.12[医药卫生—口腔医学]