Current considerations for the surgical management of gallbladder adenomas  

作　　者：Efstathios T Pavlidis Ioannis N Galanis Theodoros E Pavlidis 

机构地区：[1]The Second Department of Propaedeutic Surgery,Hippokration General Hospital,School of Medicine,Aristotle University of Thessaloniki,Thessaloniki 54642,Greece

出　　处：《World Journal of Gastrointestinal Surgery》2024年第6期1507-1512,共6页世界胃肠外科杂志（英文版）（电子版）

摘　　要：Gallbladder adenomas are rare lesions(0.5%)associated with potential malignant transformation,particularly with gallbladder adenomas that are≥1 cm in size.Early detection and management are crucial for preventing lethal carcinoma de-velopment.These polyps can often be distinguished from the more often nonneo-plastic cholesterol pseudopolyps(5%-10%),which are benign.Ultrasonography is the first-line tool for initial diagnosis and follow-up when indicated.The question is whether cholecystectomy is always necessary for all adenomas.The manage-ment of gallbladder adenomas is determined according to the size of the tumor,the growth rate of the tumor,the patient’s symptoms and whether risk factors for malignancy are present.Adenomas≥1 cm in size,an age>50 years and a familial history of gallbladder carcinoma are indications for immediate laparoscopic chole-cystectomy.Otherwise,ultrasound follow-up is indicated.For adenomas 6-9 mm in size,the absence of≥2 mm growth at 6 months,one year,and two years,as well as an adenoma sized<5 mm without existing risk factors indicates that no further surveillance is required.However,it would be preferable to individualize the management in doubtful cases.Novel interventional modalities for preserving the gallbladder need further evaluation,especially to determine the long-term outcomes.

关 键 词：Biliary diseases True neoplastic polyps Gallbladder adenomas Benign bi-liary tumors Gallbladder polyps Extrahepatic biliary neoplasms 

分 类 号：R735.8[医药卫生—肿瘤]