Application value of indocyanine green fluorescence imaging in guiding sentinel lymph node biopsy diagnosis of gastric cancer: Meta-analysis  

作　　者：Qi-Jia Zhang Zhi-Cheng Cao Qin Zhu Yu Sun Rong-Da Li Jin-Long Tong Qin Zheng 

机构地区：[1]Department of Oncology,The Second Hospital of Nanjing,Affiliated to Nanjing University of Chinese Medicine,Nanjing 210003,Jiangsu Province,China [2]Department of Gastrointestinal Surgery,Qilu Hospital of Shandong University,Jinan 250063,Shandong Province,China

出　　处：《World Journal of Gastrointestinal Surgery》2024年第6期1883-1893,共11页世界胃肠外科杂志（英文版）（电子版）

摘　　要：BACKGROUND Gastric cancer is a common malignant tumor of the digestive system worldwide,and its early diagnosis is crucial to improve the survival rate of patients.Indocyanine green fluorescence imaging(ICG-FI),as a new imaging technology,has shown potential application prospects in oncology surgery.The meta-analysis to study the application value of ICG-FI in the diagnosis of gastric cancer sentinel lymph node biopsy is helpful to comprehensively evaluate the clinical effect of this technology and provide more reliable guidance for clinical practice.AIM To assess the diagnostic efficacy of optical imaging in conjunction with indocya-nine green(ICG)-guided sentinel lymph node(SLN)biopsy for gastric cancer.METHODS Electronic databases such as PubMed,Embase,Medline,Web of Science,and the Cochrane Library were searched for prospective diagnostic tests of optical imaging combined with ICG-guided SLN biopsy.Stata 12.0 software was used for analysis by combining the"bivariable mixed effect model"with the"midas"command.The true positive value,false positive value,false negative value,true negative value,and other information from the included literature were extracted.A literature quality assessment map was drawn to describe the overall quality of the included literature.A forest plot was used for heterogeneity analysis,and P<0.01 was considered to indicate statistical significance.A funnel plot was used to assess publication bias,and P<0.1 was considered to indicate statistical significance.The summary receiver operating characteristic(SROC)curve was used to calculate the area under the curve(AUC)to determine the diagnostic accuracy.If there was interstudy heterogeneity(I2>50%),meta-regression analysis and subgroup analysis were performed.analysis were performed.RESULTS Optical imaging involves two methods:Near-infrared(NIR)imaging and fluorescence imaging.A combination of optical imaging and ICG-guided SLN biopsy was useful for diagnosis.The positive likelihood ratio was 30.39(95%CI:0.92-1.00),the sensitivity was 0.95

关 键 词：Gastric neoplasms Sentinel lymph nodes Near infrared imaging Fluorescence imaging Indocyanine green META-ANALYSIS 

分 类 号：R73[医药卫生—肿瘤]