Reproducibility study of intravoxel incoherent motion and apparent diffusion coefficient parameters in normal pancreas  

作　　者：Xiang Liu Yi-Feng Wang Xiao-Hui Qi Zhi-Lei Zhang Jiang-Yang Pan Xue-Li Fan Yu Du Ying-Min Zhai Qi Wang 

机构地区：[1]Department of CT and MRI,The Fourth Hospital of Hebei Medical University,Shijiazhuang 050000,Hebei Province,China

出　　处：《World Journal of Gastrointestinal Surgery》2024年第7期2031-2039,共9页世界胃肠外科杂志（英文版）（电子版）

基　　金：Supported by The Fourth Hospital of Hebei Medical University,No.20210423.

摘　　要：BACKGROUND The consistency of pancreatic apparent diffusion coefficient(ADC)values and intravoxel incoherent motion(IVIM)parameter values across different magnetic resonance imaging(MRI)devices significantly impacts the patient’s diagnosis and treatment.AIM To explore consistency in image quality,ADC values,and IVIM parameter values among different MRI devices in pancreatic examinations.METHODS This retrospective study was approved by the local ethics committee,and informed consent was obtained from all participants.In total,22 healthy volunteers(10 males and 12 females)aged 24-61 years(mean,28.9±2.3 years)underwent pancreatic diffusion-weighted imaging using 3.0T MRI equipment from three vendors.Two independent observers subjectively scored image quality and measured the pancreas’s overall ADC values and signal-to-noise ratios(SNRs).Subsequently,regions of interest(ROIs)were delineated for the IVIM parameters(true diffusion coefficient,pseudo-diffusion coefficient,and perfusion fraction)using post-processing software.These ROIs were on the head,body,and tail of the pancrease.The subjective image ratings were assessed using the kappa consistency test.Intraclass correlation coefficients(ICCs)and mixed linear models were used to evaluate each device’s quantitative parameter values.Finally,a pairwise analysis of IVIM parameter values across each device was performed using Bland-Altman plots.RESULTS The Kappa value for the subjective ratings of the different observers was 0.776(P<0.05).The ICC values for interobserver and intra-observer agreements for the quantitative parameters were 0.803[95% confidence interval(CI):0.684-0.880]and 0.883(95%CI:0.760-0.945),respectively(P<0.05).The ICCs for the SNR between different devices was comparable(P>0.05),and the ICCs for the ADC values from different devices were 0.870,0.707,and 0.808,respectively(P<0.05).Notably,only a few statistically significant inter-device agreements were observed for different IVIM parameters,and among those,the ICC values were generally low.Th

关 键 词：Intravoxel incoherent motion PANCREAS Image quality Consistency test 

分 类 号：R576[医药卫生—消化系统]