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作 者:Xiuyun Lu Jiaying Cao Yaozu Liu Jingqin Ma Jianjun Luo Yi Dong Wenping Wang
机构地区:[1]Shanghai Institute of Medical Imaging,Shanghai,China [2]Department of Ultrasound,Zhongshan Hospital,Fudan University,Shanghai,China [3]Department of Ultrasound,Xinhua Hospital Affiliated to Shanghai Jiaotong University School of Medicine,Shanghai,China [4]Department of Interventional Radiology,Zhongshan Hospital,Fudan University,Shanghai,China [5]National Clinical Research Center for Interventional Medicine,Zhongshan Hospital,Fudan University,Shanghai,China
出 处:《Portal Hypertension & Cirrhosis》2024年第2期124-127,共4页门静脉高压与肝硬化(英文)
基 金:Clinical Research Plan of SHDC,Grant/Award Numbers:SHDC2020CR4060,SHDC2020CR1031B;Shanghai Pujiang Program,Grant/Award Number:2020PJD008;National Natural Science Foundation of China,Grant/Award Number:82071942。
摘 要:Giant hepatic cysts may lead to impaired liver function by compressing surrounding tissue,resulting in symptoms such as nausea or portal hypertension.Subharmonic-aided pressure estimation(SHAPE)offers a noninvasive method for quantitatively estimating pressure and monitoring interstitial fluid pressure.A 55-year-old female patient with giant hepatic cysts was admitted to our hospital with elevated protein electrophoretic gamma levels,likely caused by compression of important liver vessels by the cysts.Before surgery,B-mode ultrasound(BMUS)revealed multiple anechoic cystic lesions with thin,smooth walls in the right lobe.In SHAPE,the curve of the portal vein was lower than that of the hepatic vein,which is absolutely different from a healthy volunteer in our previous SHAPE study.It suggested that the patient may have had portal hypertension.Three days after laparoscopic fenestration and drainage of hepatic cysts,the size of the largest cyst had decreased on BMUS and protein electrophoretic gamma levels had normalized.While the curve of the portal vein remained lower than that of the hepatic vein,the difference between them had decreased compared to presurgery levels.SHAPE shows promise as a tool for noninvasively estimating portal hypertension and improving prognosis assessment in patients.
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