恶性梗阻性黄疸患者胆肠吻合术后发生上消化道梗阻的影响因素分析  

Influencing factors of upper gastrointestinal obstruction in patients with malignant obstructive jaundice after biliary-enteric anastomosis

作　　者：王刘冬 Wang Liudong(Ward of Biliary Tract Disease,Department of General Surgery,Nanyang Central Hospital,Nanyang 473000,China)

机构地区：[1]南阳市中心医院普通外科胆道病区,南阳473000

出　　处：《中国实用医刊》2024年第8期62-65,共4页Chinese Journal of Practical Medicine

摘　　要：目的探讨恶性梗阻性黄疸患者胆肠吻合术后发生上消化道梗阻的影响因素。方法病例对照研究。抽取2021年9月至2023年9月南阳市中心医院收治的恶性梗阻性黄疸患者106例,均给予胆肠吻合术治疗,依据术后是否发生上消化道梗阻分为发生组(25例)和未发生组(81例)。比较两组临床资料,采用多因素Logistic回归分析恶性梗阻性黄疸患者胆肠吻合术后发生上消化道梗阻的影响因素。结果发生组年龄、淋巴结转移占比、白细胞计数高于未发生组,白蛋白水平低于未发生组,P<0.05。多因素Logistic回归分析结果显示,高龄、淋巴结转移、高白细胞计数是恶性梗阻性黄疸患者胆肠吻合术后发生上消化道梗阻的危险因素(OR>1,P<0.05),高白蛋白是保护因素(OR<1,P<0.05)。结论恶性梗阻性黄疸患者胆肠吻合术后仍有一定的上消化道梗阻发生风险,且年龄、淋巴结转移、白蛋白水平、白细胞计数是恶性梗阻性黄疸患者胆肠吻合术后发生上消化道梗阻的影响因素。Objective To investigate the influencing factors of upper gastrointestinal obstruction in patients with malignant obstructive jaundice after biliary-enteric anastomosis.Methods A total of 106 patients with malignant obstructive jaundice admitted to Nanyang Central Hospital from September 2021 to September 2023 were selected for the case-control study,and all of them were treated by biliary-enteric anastomosis surgery.According to development of upper gastrointestinal obstruction after surgery,the selected patients were divided into the occurrence group(25 cases)and the non occurrence group(81 cases).The clinical data of the two groups were compared.Multivariate logistic regression analysis was used to analyze the influencing factors of upper gastrointestinal obstruction after biliary-enteric anastomosis in patients with malignant obstructive jaundice.Results The age,proportion of lymph node metastasis,and white blood cell count in the occurrence group were higher than those in the non occurrence group,while the level of albumin was lower than that in the non occurrence group,P<0.05.The results of multivariate logistic regression analysis showed that older age,concurrent lymph node metastasis and higher white blood cell count were risk factors for upper gastrointestinal obstruction in patients with malignant obstructive jaundice after biliary-enteric anastomosis(OR>1,P<0.05),while albumin level was a protective factor for it(OR<1,P<0.05).Conclusions Patients with malignant obstructive jaundice still have a certain risk of upper gastrointestinal obstruction after biliary-enteric anastomosis.Age,lymph node metastasis,albumin level,and white blood cell count are influencing factors for the occurrence of upper gastrointestinal obstruction in patients with malignant obstructive jaundice after biliary-enteric anastomosis.

关 键 词：梗阻性黄疸 恶性 胆肠吻合术 上消化道梗阻 影响因素 

分 类 号：R735[医药卫生—肿瘤]