DTI联合DWI对急性脑梗死早期缺血半暗带的定量评估价值  

Quantitative Evaluation Value of DTI Combined with DWI for Early Ischemic Penumbra of Acute Cerebral Infarction

作　　者：李静[1] 张嘉俊 王可 LI Jing;ZHANG Jigjun;WANG Ke(Department of Medical Imaging,Zhengzhou Seventh People's Hospital,Zhengzhou450016,China;Department of Medical Imaging,the Fifth Affiliated Hospital of Zhengzhou University,Zhengzhou 450052,China)

机构地区：[1]郑州市第七人民医院医学影像科,河南郑州450016 [2]郑州大学第五附属医院医学影像科,河南郑州450052

出　　处：《临床医学工程》2024年第7期785-786,共2页Clinical Medicine & Engineering

摘　　要：目的分析磁共振弥散张量成像(DTI)联合弥散加权成像(DWI)对急性脑梗死(ACI)早期缺血半暗带(IP)的定量评估价值。方法选取ACI患者80例,均行磁共振DTI和DWI检查,根据患者发病时间将其分为超急性期组(<6h,n=24)、急性期组(6~24h,n=26)和亚急性期组(24~72h,n=30),比较ACI患者梗死中心区、IP区、对侧镜像区的平均扩散系数(DCavg)、表观扩散系数(ADC)、异性指数(FA)值,并比较ACI患者不同发病时期IP区的rDCavg、rADC、rFA值。结果ACI患者不同区域DCavg、ADC、FA值比较:梗死中心区<IP区<对侧镜像区(P<0.05)。ACI患者不同发病时期IP区rDCavg、rADC、rFA值比较:超急性期组>急性期组>亚急性期组(P<0.05)。结论DTI联合DWI检查的相关定量参数对于ACI早期IP具有较高的评估价值,临床可借鉴应用。Objective To analyze the quantitative evaluation value of magnetic resonance diffusion tensor imaging(DTI)combined with diffusion weighted imaging(DWI)for early ischemic penumbra(IP)of acute cerebral infarction(ACI).Methods 80 ACI patients were selected and given magnetic resonance DTI and DWI examination.According to the onset time,the patients were divided into hyperacute group(<6 h,n=24),acute group(6~24 h,n=26)and subacute group(24~72 h,n=30).The DCavg,ADC and FA values of infarct center area,IP area and contralateral mirror area in ACI patients were compared,and the rDCavg,rADC and rFA values of IP area in ACI patients at different onset stages were compared.Results The comparison of DCavg,ADC,and FA values in different regions of ACI patients showed that the infarct center area<IP area<contralateral mirror area(P<0.05).The comparison of rDCavg,rADC,and rFA values in the IP area of ACI patients at different onset stages showed that hyperacute group>acute group>subacute group(P<0.05).Conclusions The relevant quantitative parameters of DTI combined with DWI have higher evaluation value for early IP of ACI,which can be applied clinicallyfor reference.

关 键 词：急性脑梗死 缺血半暗带 弥散张量成像 弥散加权成像 定量参数 评估价值 

分 类 号：R743.33[医药卫生—神经病学与精神病学]