双相情感障碍抑郁发作患者出院后1年内再入院的影响因素  

Influencing factors of readmission within 1 year after discharge in patients with bipolar disorder and depressive episodes

作　　者：赵昕 王雪[1,2] 袁晓菲[1,2] 王巍巍[1,2] 徐劲节[1,2] 吴涵 姜玮[1,2] ZHAO Xin;WANG Xue;YUAN Xiaofei;WANG Weiwei;XU Jinjie;WU Han;JIANG Wei(Beijing Anding Hospital of Capital Medical University,National Medical Center for Mental Disease,Key Laboratory of Diagnosis and Treatment of Mental Disorders,Beijing 100088,China;Advanced Innovation Center for Human Brain Protection of Capital Medical University,Beijing 100069,China)

机构地区：[1]首都医科大学附属北京安定医院,国家精神疾病医学中心,国家精神心理疾病临床医学研究中心,精神疾病诊断与治疗北京市重点实验室,北京100088 [2]首都医科大学人脑保护高精尖创新中心,北京100069

出　　处：《中国民康医学》2024年第14期1-3,共3页Medical Journal of Chinese People’s Health

基　　金：北京市属医院科研培育计划项目(PX2020074);首都卫生发展科研专项项目(首发2020-2-2122)。

摘　　要：目的:分析双相情感障碍抑郁发作患者出院后1年内再入院的影响因素。方法:选取2018—2022年首都医科大学附属北京安定医院收治的1924例双相情感障碍抑郁发作患者进行横断面研究。收集患者临床资料,统计出院后1年内再入院情况,根据患者是否再入院将其分为再入院组和未再入院组。采用COX多元回归分析双相情感障碍抑郁发作患者出院后1年内再入院的影响因素。结果:1924例双相情感障碍抑郁发作患者出院后1年内再入院347例,再入院率为18.04%(347/1924);两组性别、文化程度、婚姻状况、精神疾病家族史、使用抗抑郁药物治疗情况比较,差异均无统计学意义(P>0.05);两组年龄、既往住院次数、病程、伴精神病性症状、心境稳定剂应用方式比较,差异均有统计学意义(P<0.05);COX多元回归分析结果显示,年龄较大、既往住院次数多、伴精神病性症状、单用一种心境稳定剂均为双相情感障碍抑郁发作患者出院后1年内再入院的危险因素(P<0.05)。结论:年龄较大、既往住院次数多、伴精神病性症状、单用一种心境稳定剂均为双相情感障碍抑郁发作患者出院后1年内再入院的危险因素。Objective:To analyze influencing factors of readmission within 1 year after discharge in patients with bipolar disorder and depressive episodes.Methods:A cross-sectional study was conducted on 1924 patients with bipolar disorder and depressive episodes admitted to Beijing Anding Hospital of Capital Medical University from 2018 to 2022.The clinical data of these patients were collected.The readmission within 1 year after discharge was statistically analyzed.They were divided into readmission group and non-readmission group according to whether they were readmitted.COX multiple regression was used to analyze the influencing factors of readmission within 1 year after discharge in the patients with bipolar disorder and depressive episodes.Results:Among the 1924 patients with bipolar disorder and depressive episodes,347 were readmitted within 1 year after discharge,with a readmission rate of 18.04%(347/1924).There were no statistically significant differences in terms of gender,educational level,marital status,family medical history,and treatment with antidepressants between the two groups(P>0.05).There were statistically significant differences in terms of age,number of previous hospitalizations,course of disease,combined psychiatric symptoms,and use of mood stabilizers between the two groups(P<0.05).The COX multiple regression analysis showed that age,number of previous hospitalizations,combined psychiatric symptoms,and use of mood stabilizers were all risk factors for readmission within 1 year after discharge in the patients with bipolar disorder and depressive episodes(P<0.05).Conclusions:Age,number of previous hospitalizations,combined psychiatric symptoms,and use of mood stabilizers are the risk factors for readmission within 1 year after discharge in the patients with bipolar disorder and depressive episodes.

关 键 词：双相情感障碍 抑郁发作 再入院 影响因素 

分 类 号：R749[医药卫生—神经病学与精神病学]