肠外营养相关性肝病研究进展  

Research progress of parenteral nutrition-associated liver disease

作　　者：刘欢 杨婷婷 周金花 吴冬 LIU Huan;YANG Tingting;ZHOU Jinhua;WU Dong(Department of Emergency Medicine,Jining First People s Hospital,Shandong First Medical University,Jining,Shandong 272000,China;不详)

机构地区：[1]山东第一医科大学附属济宁第一人民医院急诊内科,山东济宁272000 [2]菏泽市第二人民医院消化内科,山东菏泽274000 [3]山东第一医科大学附属济宁第一人民医院呼吸与危重症医学科,山东济宁272000

出　　处：《中国临床研究》2024年第7期1128-1130,共3页Chinese Journal of Clinical Research

摘　　要：肠外营养相关性肝病(PNALD)是指接受全肠外营养患者出现的一系列肝病,从肝酶异常到脂肪变性,再到纤维化,直至最终出现肝硬化。PNALD的发病机制是多因素的,目前尚不完全清楚。PNALD没有具体的治疗方法,其预防和治疗的管理策略取决于对危险因素的了解。本文就PNALD的发病机制和治疗进展进行综述。Parenteral nutrition-associated liver disease(PNALD)refers to a range of liver diseases that occur in patients who receive total parenteral nutrition,ranging from abnormal liver enzymes to steatosis,fibrosis,and eventually cirrhosis.The pathogenesis of PNALD is multifactorial and is not completely understood.There is no specific treatment for PNALD,and management strategies for its prevention and treatment depend on knowledge of the risk factors.This article reviews the pathogenesis and treatment progress of PNALD.

关 键 词：肠外营养相关性肝病 肠衰竭 肝硬化 肠外营养相关胆汁淤积症 短肠综合征 

分 类 号：R575.22[医药卫生—消化系统]