光敏性枕叶癫痫的研究进展  

Recent advance on photosensitive occipital lobe epilepsy

作　　者：王雪梅 李敏婷 唐芬[1] 秦兵 WANG Xuemei;LI Minting;TANG Fen;QIN Bing(Epilepsy Center,Department of Neurosurgery,The First Hospital of Jinan University,Guangzhou 510630,China)

机构地区：[1]暨南大学附属第一医院神经外科·癫痫中心,广州510630

出　　处：《癫痫杂志》2024年第4期328-331,共4页Journal of Epilepsy

基　　金：暨南大学临床医学研究院高端人才引进项目(89018041);国家留学基金(2019067885005)。

摘　　要：光敏性枕叶癫痫(Photosensitive occipital lobe epilepsy,POLE)是一种各年龄段均可起病的、罕见的特发性反射性局灶性癫痫,其特征是闪光刺激(闪烁的阳光、视频游戏、电视广告和节目等)诱发的枕叶发作。间断闪光刺激诱发试验可见光阵发性反应;发作期脑电图可见枕区起源的棘波节律。影像学无明显异常。对抗癫痫发作药物反应良好,预后佳。本文综述POLE近年来相关研究进展,以帮助临床医生认识该综合征,降低漏诊率和误诊率。Photosensitive occipital lobe epilepsy(POLE)is a rare idiopathic reflex focal epilepsy that can occur in all age groups.It is characterized by occipital lobe seizures induced by flashing stimuli(flashing sunlight,video games,TV commercials and programs,etc.).Photoparoxysmal response on EEG is induced by intermittent photic stimulation;Ictal EEG shows rapid spike rhythms are originated from the occipital region.There are no obvious abnormalities in brain image.POLE responds well to anti-seizure medications and has a good prognosis.This article reviews the research progress on POLE in order to improve the clinician’s understanding and reduce the rates of missed diagnosis and misdiagnosis.

关 键 词：光敏性枕叶癫痫 视觉诱发癫痫 闪光刺激 

分 类 号：R742.1[医药卫生—神经病学与精神病学]