Effects of pressing moxibustion at Baihui(GV 20)and Guanyuan(CV 4)on cognitive impairment and serum levels of Aβ_(1-42),tau,P-tau in patients with mild to moderate Alzheimer's disease  

作　　者：杨淑荃 YANG Shuquan(Dept Acupunct Moxib,2nd TCM Hosp,Guangdong Prov,Guangzhou 510095)

机构地区：[1]Dept Acupunct Moxib,2nd TCM Hosp,Guangdong Prov,Guangzhou 510095

出　　处：《China Medical Abstracts(Internal Medicine)》2024年第2期70-71,共2页中国医学文摘（内科学分册（英文版）

摘　　要：Objective To compare the effects of pressing moxibustion at Baihui(GV 20)and Guanyuan(CV 4)combined with donepezil hydrochloride tablets and donepezil hydrochloride tablets alone on cognitive impairment in patients with mild to moderate Alzheimer's disease(AD),and to explore the mechanism of pressing moxibustion in the treatment of mild to moderate AD from the serum levels ofβ-amyloid 1-42(Aβ1-42),microtubule-associated protein tau and phosphorylated tau(P-tau).Methods A total of 76 patients with mild to moderate AD were randomly divided into an observation group(38 cases,4 cases dropped out)and a control group(38 cases,2 cases dropped out).Patients in the control group were given oral donepezil hydrochloride tablets(5 mg each time,once a day).On the basis of the control group,patients in the observation group were treated with pressing moxibustion at Baihui(GV 20)and Guanyuan(CV 4),5 cones per acupoint,once every other day,three times a week.Both groups were treated for 8 weeks.

关 键 词：MOXIBUSTION TABLETS TAU 

分 类 号：R246.6[医药卫生—针灸推拿学]