慢性肝病患者血清25-羟基维生素D与肝性脑病的相关性研究进展  

Research progress on the correlation between serum 25-hydroxy vitamin D and hepatic encephalopathy in patients with chronic liver disease

作　　者：高晓琴 周丹 张立婷[1] 李敏[1] Gao Xiaoqin;Zhou Dan;Zhang Liting;Li Min(Department of Hepatology,Lanzhou University First Hospital,Gansu Lanzhou 730000,China)

机构地区：[1]兰州大学第一医院肝病科,甘肃兰州730000

出　　处：《中国肝脏病杂志（电子版）》2024年第2期17-21,共5页Chinese Journal of Liver Diseases：Electronic Version

基　　金：甘肃省教育科技创新项目(2022B-004);兰州大学第一医院院内青年基金项目(ldyyyn2021-88);兰州大学第一医院院内青年基金项目(ldyyyn2021-77)。

摘　　要：肝性脑病(hepatic encephalopathy,HE)是慢性肝病(chronic liver disease,CLD)的严重临床并发症,其与多种因素有关,包括胃肠道出血、便秘和血电解质紊乱等。目前,25-羟基维生素D缺乏已被确定为与HE发展相关的因素之一。本文现对CLD合并HE患者25-羟基维生素D水平及25-羟基维生素D缺乏与HE间的相关性进行综述。Hepatic encephalopathy(HE)is a serious clinical complication of chronic liver disease(CLD).It is associated with a variety of factors,including gastrointestinal bleeding,constipation and blood electrolyte disorders.Currently,25-hydroxyvitamin D deficiency has been found to be associated with the development of HE.This paper reviewed the research progress of 25-hydroxyvitamin D levels in CLD patients complicated with HE and the correlation between 25-hydroxyvitamin D deficiency and HE.

关 键 词：25-羟基维生素D 维生素D 慢性肝病 肝性脑病 

分 类 号：R575[医药卫生—消化系统] R747.9[医药卫生—内科学]