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作 者:王效良 Wang Xiaoliang(Department of Radiotherapy Yancheng First Hospital Affiliated to Nanjing University School of Medicine(Yancheng First People's Hospital),Yancheng 224000,China)
机构地区:[1]南京大学医学院附属盐城第一医院(盐城市第一人民医院)放疗科,江苏盐城224000
出 处:《实用妇科内分泌电子杂志》2024年第17期11-13,共3页Electronic Journal of Practical Gynecological Endocrinology
摘 要:目的探究容积旋转调强放疗(VMAT)应用于宫颈癌患者中的效果。方法选取55例宫颈癌患者,根据放疗方法不同分为观察组(28例,接受VMAT治疗)与对照组(27例,接受固定野动态调强放疗,FF-IMRT)。对比两组肿瘤周围组织的受照情况及急性血液毒性发生情况。结果观察组剂量梯度指数(DGI)数值明显低于对照组(P<0.05)。观察组急性血液毒性发生率7.14%明显低于对照组的33.33%(P<0.05)。结论建议宫颈癌患者在术后接受VMAT治疗,相比FF-IMRT治疗,可以减少对正常组织的辐射剂量,还可预防急性血液毒性反应的发生。Objective To explore the effect of volume rotation intensity modulated radiotherapy(VMAT)in patients with cervical cancer.Methods 55 patients with cervical cancer were selected and divided into observation group(28 cases receiving VMAT treatment)and control group (27 cases) receiving fixed-field dynamic intensity modulated radiotherapy(FF-IMRT)according to different radiotherapy methods.The exposure of the surrounding tissues and the occurrence of acute hematotoxicity were compared between the two groups.Results The dose gradient index(DGI)of the observation group was significantly lower than that of the control group(P<0.05).The incidence of acute hematotoxicity in the observation group(7.14%)was significantly lower than that in the control group(33.33%)(P<0.05).Conclusion It is recommended that patients with cervical cancer receive VMAT treatment after surgery,which can reduce the radiation dose to normal tissues and prevent acute blood toxicity reaction compared with FF-IMRT treatment.
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