重组人干扰素α2b阴道泡腾胶囊治疗宫颈高危型HPV感染的临床研究  

Recombinant Human Interferon a2b Vaginal Effervescent Capsules for the Clinical Treatment of High-Risk HPV Infections in the Cervix

作　　者：陆安 宗俊杰[2] 陈彩雯 Lu An;Zong Junjie;Chen Caiwen(Department of Obstetrics and Gynecology,Yixing People's Hospital,Yixing 214200,China;Department of Endocrinology,Yixing People's Hospital,Yixing 214200,China)

机构地区：[1]宜兴市人民医院妇产科,江苏宜兴214200 [2]宜兴市人民医院内分泌科,江苏宜兴214200

出　　处：《实用妇科内分泌电子杂志》2024年第17期55-57,共3页Electronic Journal of Practical Gynecological Endocrinology

摘　　要：目的研究宫颈高危型HPV感染应用重组人干扰素α2b阴道泡腾胶囊治疗的作用。方法选取100例宫颈高危型HPV感染患者,根据随机数字表法分为研究组与一般组,各50例。一般组定期随访不做任何处理,研究组采用重组人干扰素α2b阴道泡腾胶囊治疗。比较两组转阴情况、治疗前后生活质量评分。结果研究组转阴率高于(62.00 vs 22.00)%一般组(P<0.05)。治疗后,研究组生活质量评分(75.98±10.52 vs 85.98±11.03)分高于一般组(P<0.05)。结论宫颈高危型HPV感染患者实施重组人干扰素α2b阴道泡腾胶囊治疗,可有效提高转阴率,改善患者生活质量,值得临床推广。Objective Study the Effect of Treating High-Risk HPV Infections of the Cervix with Recombinant Human Interferon a 2b Combined with Vaginal Effervescent Capsules.Methods A total of 100 patients with high-risk HPV infections of the cervix were selected and divided into a study group and a general group,each consisting of 50 individuals,using a random digit table method.The general group received regular follow-up without any treatment,while the study group was treated with recombinant human interferon a 2b vaginal effervescent capsules.The study compared the conversion rates to negative and the quality of life scores before and after treatment between the two groups.Results The negative conversion rate in the study group was higher than that in the general group(62.00%vs 22.00%,P<0.05).After treatment,the quality of life scores in the study group(85.98±11.03)were higher than those in the general group(75.98±10.52),with a significant difference(P<0.05).Conclusion Recombinant human interferon a2b vaginal effervescent capsule can effectively improve the conversion rate and the quality of life of patients with high-risk HPV infection of cervix,which is worthy of clinical promotion.

关 键 词：重组人干扰素α2b阴道泡腾胶囊 转阴 高危型人乳头瘤病毒 

分 类 号：R737.33[医药卫生—肿瘤]