HPV联合液基细胞学检测宫颈病变的临床意义分析  

Analysis of clinical significance of HPV combined with liquid-based cytology to detect cervical lesions

作　　者：倪胜南 陈一鸣 Ni Shengnan;Chen Yiming(Department of Laboratory,Siyang Kangda Hospital,Suqian 223700,China)

机构地区：[1]泗阳康达医院检验科,江苏宿迁223700

出　　处：《实用妇科内分泌电子杂志》2024年第17期82-84,共3页Electronic Journal of Practical Gynecological Endocrinology

摘　　要：目的分析人乳头瘤病毒(HPV)联合液基细胞学检测宫颈病变的临床意义。方法选取69例实施宫颈病变筛查的女性,对受检者应用HPV联合液基细胞学检测,观察其检测结果。结果液基细胞学检查结果与阴道镜活检病理检查结果存在一定差异,不明确意义的非典型鳞状上皮细胞(ASCUS)中依然存在一定假阴性率,本次检测为13.33%(4/30),细胞学检测的低度鳞状上皮内病变(LSIL)符合率为68.00%(17/25),细胞学检测的LSIL的符合率为78.57%(11/14),随着级别增高,其与组织病理学的符合率增加。但在宫颈癌前病变患者中也依然存在HPV感染阴性,需通过与阴道镜检查相结合以最大程度提升诊断诊断率。结论HPV联合液基细胞学检测更有利于提升宫颈病变的诊断准确率。Objective To analyze the clinical significance of human papillomavirus(HPV)combined with liquid-based cytology in detecting cervical lesions.Methods 69 women who underwent cervical screening were selected and tested by HPV combined with liquid based cytology to observe the results.Results There were some differences between the results of liquid based cytology and colposcopic biopsy,and there was still a certain false negative rate in AscUS,which was 13.33%(4/30)in this test,68.00%(17/25)in cytology and 78.57%(11/14)in cytology.The coincidence rate with histopathology increased as the grade increased.However,HPV infection is still negative in patients with cervical precancerous lesions,which needs to be combined with colposcopy to maximize the diagnostic rate.Conclusion HPV combined with liquid based cytology is more beneficial to improve the diagnostic accuracy of cervical lesions.

关 键 词：人乳头瘤病毒感染 液基细胞学 宫颈病变 临床意义 

分 类 号：R737.33[医药卫生—肿瘤]