慢性心衰患者抑郁情绪与心脏功能的关系  

The relationship between depression and cardiac function in patients with chronic heart failure

作　　者：王蕾 俞静 WANG Lei;YU Jing(Anhui Huainan Dongfang Hospital Group General Hospital,Huainan 232038,China)

机构地区：[1]安徽省淮南市东方医院集团总院,淮南232038

出　　处：《国际精神病学杂志》2024年第3期879-882,共4页Journal Of International Psychiatry

摘　　要：目的探讨慢性心衰患者抑郁与心脏功能的关系。方法选择2019年1月~2023年1月我院84例慢性心衰患者,采用抑郁自评量表(SDS)进行抑郁症状筛查,设为抑郁组与非抑郁组。比较两组患者一般资料、左心室收缩末期及舒张末期内径(LVESD、LVEDD)、左心室射血分数(LVEF)等心脏功能指标以及纽约心脏病协会(NYHA)心脏功能分级。采用二元Logistic回归分析调查抑郁症与心脏功能指标的关系。结果84例慢性心衰筛查出抑郁32例,其中26例轻度,6例中度;抑郁组与非抑郁组年龄、合并睡眠障碍、受教育年限等资料差异具有统计学意义(P<0.05),性别、居住地、婚姻状况差异无统计学意义(P>0.05);抑郁症组LVEF显著低于非抑郁组,LVESD、LVEDD显著高于对照组(P<0.05);抑郁组NYHA分级较非抑郁组更严重(P<0.05);二元Logistic回归分析显示,年龄、合并睡眠障碍、受教育年限、LVEF、NYHA分级Ⅳ级是慢性心衰患者抑郁的影响因素。结论慢性心衰患者抑郁发生率较高,可能与LVESD、心脏功能分级有关。Objective To explore the relationship between depression and cardiac function in patients with chronic heart failure.Methods Eighty-four patients with chronic heart failure in our hospital from January 2019 to January 2023 were selected as the study subjects.The self-rating depression scale(SDS)were used to depression screening,and they was divided into the depression group and the non-depression group.General information,the left ventricular end-systolic and end-diastolic diameter(LVESD,LVEDD),left ventricular ejection fraction(LVEF)and other cardiac function indexes of the two groups and the New York Heart Association(NYHA)cardiac function classification were compared.The binary logistic regression were used to analyze the relationship between cognitive dysfunction and cardiac function index.Results Among 84 cases of chronic heart failure,32 cases of depression were screened,of which 26 cases were mild and 6 cases were moderate.There were statistically significant differences in age,sleep disorder and years of education between depression group and non-depression group(P<0.05),but no statistically significant differences in gender,residence and marital status between depression group and non-depression group(P>0.05).LVEF in depression group was significantly lower than that in non-depression group,LVESD and LVEDD were significantly higher than those in control group(P<0.05).NYHA grading of depression group was more serious than that of non-depression group(P<0.05).Binary logistic regression analysis showed that age,combined sleep disorders,years of education,LVEF and NYHA gradeⅣwere the influencing factors of depression in patients with chronic heart failure.Conclusion The incidence rate of depression in patients with chronic heart failure is high,which may be related to LVESD and cardiac function grading.

关 键 词：慢性心衰 抑郁症 心脏功能 

分 类 号：R749.99[医药卫生—神经病学与精神病学]