局限期小细胞肺癌的放射治疗进展  

Radiotherapy advances in limited-stage small cell lung cancer

作　　者：曲皎月 汪庚明[1] QU jiaoyue;WANG Gengming(Department of Radiotherapy,the First Affiliated hospital of Bengbu Medical College,Bengbu 233000,China)

机构地区：[1]蚌埠医学院第一附属医院放疗科,安徽蚌埠233000

出　　处：《沈阳医学院学报》2024年第4期409-415,共7页Journal of Shenyang Medical College

摘　　要：当前,同步放化疗及预防性颅脑照射是局限期小细胞肺癌的标准治疗方案。尽管其疗效明显,但仍有1/3的患者会出现局部复发。为探讨如何最大程度控制局部复发及提高生存期,本文分析了局限期小细胞肺癌放射治疗的研究现状,探索其最佳放射时机、靶区、剂量、分割方式,及预防性颅脑照射。此外,还对局限期小细胞肺癌新兴的放射治疗联合免疫治疗进行了概述。At present,concurrent chemoradiotherapy and prophylactic craniocerebral irradiation are the standard treatment for limited-stage small cell lung cancer.Despite its obvious efficacy,1/3 of patients still have local recurrence.In order to explore how to maximize control of local recurrence and improve survival,this article reviews the current status of radiotherapy for limited-stage small cell lung cancer,and explores its optimal timing,target area,dose,segmentation,and prophylactic craniocerebral irradiation.In addition,emerging therapies of radiotherapy combined with immunotherapy in limited-stage small cell lung cancer are also reviewed.

关 键 词：小细胞肺癌 局限期 放射治疗 免疫治疗 

分 类 号：R734.2[医药卫生—肿瘤]