OCTA在早期糖尿病视网膜病变诊断中的应用及特异度、灵敏度分析  

Application, Specificity and Sensitivity of OCTA in the Diagnosis of Early Diabetic Retinopathy

作　　者：黄玉苗[1] 林水龙[1] 陈雅珍 HUANG Yumiao;LIN Shuilong;CHEN Yazhen(Department of Ophthalmology,Jinjiang Hospital(Shanghai 6th Hospital,Fujian Hospital),Jinjiang 362200,Fujian,China)

机构地区：[1]晋江市医院(上海六院福建医院)眼科,福建晋江362200

出　　处：《糖尿病新世界》2024年第9期173-175,共3页Diabetes New World Magazine

摘　　要：目的分析光学相干断层扫描血管成像(optical coherence tomography angiography,OCTA)对早期糖尿病视网膜病变(diabetic retinopathy,DR)诊断中的价值。方法选取晋江市医院眼科于2023年1月—2024年1月收治的94例(176眼)疑似DR患者为研究对象,均开展OCTA检查和眼底荧光素血管造影(fundus fluorescein angiography,FFA)。将FFA结果作为金标准,评价OCTA对早期DR的诊断价值,通过kappa一致性检验分析OCTA诊断DR与FFA结果的一致性。结果FFA共检出122眼DR,54眼无DR;OCTA共检出119眼DR,57眼无DR。OCTA诊断早期DR的灵敏度、特异度、准确度、阳性预测值、阴性预测值分别为94.26%、92.59%、93.75%、96.64%、87.72%。kappa检验结果可知,OCTA诊断DR与FFA结果的一致性较强(kappa=0.792)。结论OCTA诊断DR与FFA结果的一致性较强,有助于诊断早期DR,具有较高灵敏度、特异度。Objective To analyze the value of optical coherence tomography angiography(OCTA)in the diagnosis of early diabetic retinopathy(DR).Method A total of 94 patients(176 eyes)with suspected DR treated in the Department of Ophthalmology of Jinjiang Hospital from January 2023 to January 2024 were selected as the study objects.Each patient underwent OCTA examination and fundus fluorescein angiography(FFA).The FFA results were used as the gold standard to evaluate the value of OCTA in the diagnosis of early DR,and the consistency of OCTA diagnosis of DR and FFA results was analyzed by kappa consistency test.Results FFA detected 122 eyes with DR And 54 eyes without DR.A total of 119 eyes with DR and 57 eyes without DR were detected by OCTA.The sensitivity,specificity,accuracy,positive predictive value and negative predictive value of OCTA in diagnosing early DR were 94.26%,92.59%,93.75%,96.64%and 87.72%respectively.The results of kappa test showed strong consistency between OCTA diagnosis of DR And FFA results(kappa=0.792).Conclusion The consistency between OCTA diagnosis of DR and FFA results is strong,which is helpful for the diagnosis of early DR,and has high sensitivity and specificity.

关 键 词：光学相干断层扫描血管成像 糖尿病性视网膜病变 眼底荧光素血管造影 

分 类 号：R77[医药卫生—眼科]