立体定向脑电图引导下电刺激引起微笑与欢笑2例  

Stereotactic electroencephalography-guided electrical stimulation-induced smile and laughter:a report of two cases

作　　者：梁新宜 谢延风[1] 石全红[1] 詹彦[1] 蒋理[1] 但炜[1] LIANG Xinyi;XIE Yanfeng;SHI Quanhong;ZHAN Yan;JIANG Li;DAN Wei(Department of Neurosurgery of the First Affiliated Hospital of Chongqing Medical University,Chongqing 400016,China)

机构地区：[1]重庆医科大学附属第一医院神经外科,重庆400016

出　　处：《中国神经精神疾病杂志》2024年第5期297-299,共3页Chinese Journal of Nervous and Mental Diseases

基　　金：国家临床重点专科建设项目经费资助[编号:(2011)170号];重庆市卫生局重点课题(编号:2012-1-008)。

摘　　要：欢笑和微笑在大脑中的产生和传播网络尚未完全清楚。本文报告2例行立体定向脑电图植入的药物难治性癫痫患者,通过电刺激分别在左侧中央前回、右侧岛短回反复诱发出微笑(不带有愉悦情绪及运动意识)及欢笑(带有与情景不相符的愉悦情绪)。该现象反映了笑的情绪及行为网络存在区别与联系。The network of laughter/smile production and propagation in the brain is not yet fully understood.In this paper,we report two cases of medically refractory epilepsy patients with stereotactic EEG implantation,in which smiles(without pleasurable emotions and motor awareness)and laughter(with situationally incompatible pleasurable emotions)were repeatedly induced by electrical stimulation in the left precentral gyrus,and the right insular short gyrus,respectively.This phenomenon reflects the existence of distinct and linked emotional and behavioral networks for laughter.

关 键 词：发笑 笑的神经网络 药物难治性癫痫 立体定向脑电图 电刺激 情感表达 扣带回 

分 类 号：R742.1[医药卫生—神经病学与精神病学] R741.044[医药卫生—临床医学]