高分辨率MRI血管壁成像评估颅内动脉粥样硬化相关缺血性卒中发病机制及治疗的研究进展  

Progress of High-Resolution Magnetic Resonance Vessel Wall Imaging in the Evaluation of Pathogenesis and Treatment of Intracranial Atherosclerosis-Related Ischemic Stroke

作　　者：王雪莲 王飞[1] 刘心成 袁涛[1] 高丽娟[1] 檀国军[3] 全冠民[1] WANG Xuelian;WANG Fei;LIU Xincheng;YUAN Tao;GAO Lijuan;TAN Guojun;QUAN Guanmin(Department of Medical Imaging,the Second Hospital of Hebei Medical University,Shijiazhuang 050000,China;不详)

机构地区：[1]河北医科大学第二医院影像科,河北石家庄050000 [2]雄安宣武医院放射与核医学科,河北雄安071702 [3]河北医科大学第二医院神经内科,河北石家庄050000

出　　处：《中国医学影像学杂志》2024年第7期747-752,共6页Chinese Journal of Medical Imaging

基　　金：河北省自然科学基金(H202206191);河北省医学适用技术跟踪项目(GZ20210015,2020054);河北省2021年老年病防治项目(361004);伦琴影像科研项目(HB-201906-001)。

摘　　要：颅内动脉粥样硬化是缺血性卒中最常见的病因,其血管壁病变类型及程度是缺血性卒中诊断和治疗的重要依据。高分辨率MRI血管壁成像可直观显示颅内血管管腔和管壁,定性和定量评估动脉粥样硬化斑块特征,包括斑块内出血、斑块强化、斑块分布等,对于缺血性卒中危险分层、发病机制、治疗和预后评估具有一定价值。本文就颅内动脉粥样硬化的高分辨率MRI血管壁成像评估研究进展,特别是斑块特征的发病机制、治疗相关信息进行综述。Intracranial atherosclerosis has been regard as the most common cause of ischemic stroke.The information of the types and degree of vascular wall lesions is important basis for the diagnosis and treatment of ischemic stroke.High-resolution MR vessel wall imaging can directly display the lumen and wall of intracranial vessels,evaluate the characteristics of atherosclerotic plaque qualitatively and quantitatively,includingintra-plaque hemorrhage,plaque enhancement,and plaque distribution.Thus,high-resolution MR vessel wall imaging may play an important role in risk stratification,pathogenesis,treatment and prognosis evaluation in ischemic stroke patients.This review summarizes the progress of high-resolution MRI vessel wall imaging in the evaluation of intracranial atherosclerosis,especially the pathogenesis of plaque features and treatment-related information.

关 键 词：缺血性卒中 动脉粥样硬化 磁共振成像 高分辨血管壁成像 综述 

分 类 号：R743.3[医药卫生—神经病学与精神病学] R445.2[医药卫生—临床医学]