药物过度使用性头痛研究现状  

The current status of medication overuse headache

作　　者：安悦铭(综述) 于生元(审校)[1] AN Yueming;YU Shengyuan(Department of Neurology,The First Medical Center,Chinese PLA General Hospital,Chinese PLA Medical School,Beijing 100853,China)

机构地区：[1]解放军总医院第一医学中心神经内科医学部,北京100853

出　　处：《中风与神经疾病杂志》2024年第7期579-581,F0002,共4页Journal of Apoplexy and Nervous Diseases

摘　　要：原发性头痛疾病的药物过度使用是一种世界性的现象,在头痛疾病的慢性化中起着重要作用。由于其治疗高成本且常与多种疾病构成共病,个人和社会的疾病负担非常大。在国际头痛疾病分类第三版中,药物过度使用性头痛(MOH)被认为是继大多数原发性头痛疾病之外的一个独立的继发性实体。本文就药物过度使用性头痛的概述、流行病学、病理生理学机制、诊断标准和治疗方案进行综述,探讨了相关的未解问题,并总结了当前关于药物过度使用性头痛的争论。The overuse of medications for primary headache disorders is a worldwide phenomenon that plays an im⁃portant role in the chronicity of headache disorders.The high treatment cost and co-morbidity with various diseases pose a heavy burden on individuals and societies.In the third edition of the International Classification of Headache Disorders,medication overuse headache(MOH)is recognized as a separate secondary entity to most primary headache disorders.This article reviews the overview,epidemiology,pathophysiological mechanisms,diagnostic criteria,and treatments of MOH,discusses some unsolved questions,and summarizes the current debate on MOH.

关 键 词：药物过度使用性头痛 继发性头痛 研究现状 膜联蛋白A1 慢性头痛 

分 类 号：R741.041[医药卫生—神经病学与精神病学] R747[医药卫生—临床医学]