卵巢Sertoli-Leydig细胞瘤临床病理特征分析(附5例)  

Ovarian Sertoli - Leydig cell tumor: A clinicopathological analysis of 5 cases

作　　者：方婉婷 明健 孟英爽 商家炜 FANG Wanting;MING Jian;MENG Yingshuang;SHANG Jiawei(Department of Pathology,Beifang Hospital of China,Liaoning Shenyang 110003,China)

机构地区：[1]北部战区总医院病理科,辽宁沈阳110003

出　　处：《现代肿瘤医学》2024年第16期3072-3077,共6页Journal of Modern Oncology

摘　　要：目的:分析卵巢Sertoli-Leydig细胞瘤(Sertoli-Leydig cell tumor, SLCT)临床病理特征。方法:报道5例卵巢sertoli-Leydig细胞瘤,总结其镜下表现,免疫组化特点,并复习文献。结果:5例卵巢Sertoli-Leydig细胞瘤,2例低分化,其余3例为高分化,中分化和网状型。Sertoli细胞,表达α-inhibin、Calretinin、WT-1,Leydig细胞α-inhibin、Claretinin表达比Sertoli细胞强,还可表达Melan-A。结论:卵巢Sertoli-Leydig细胞瘤是一种罕见的卵巢肿瘤,其形态丰富要注意和许多疾病鉴别诊断,病理医生应充分了解其病理特征避免出现误诊和漏诊。Objective:To analysis Sertoli-Leydig cell tumors,clinicopathological characteristics.Methods:We report five cases of SLCTs,summarize the microscopic appearance,immunohistorchemical features and review the literatures.Results:Five SLCTs,two cases are poorly differentiated,the other three are well-differentiated,moderately differentiated and retiform.Sertoli cell can expressα-inhibin,Calretinin,WT-1,Leydig cell expressα-inhibin,Claretinin stronger than Stertoli cell,it can also express Melan-A.Conclusion:SLCT is a rare tumor,it exhibit variety morphology we should distingush from other disease,the pathologist should well know the clinicopathological of disease to prevent from making a misdiagnosis and missed diagnosis.

关 键 词：Sertoli-Leydig细胞瘤 免疫组化 鉴别诊断 

分 类 号：R737.31[医药卫生—肿瘤]