《伤寒论》柴胡剂在现代临床应用中的比较研究  

Comparative Study on the Modern Clinical Application of Bupleurum Decoction in Treatise on Febrile Diseases

作　　者：吴梓敬 张涛[1] 杜世凡 邵琳琳 Wu Zijing;Zhang Tao;Du Shifan;Shao Linlin(Tianjin University of Chinese Medicine,Tianjin 301617,China)

机构地区：[1]天津中医药大学中医学院,天津301617

出　　处：《亚太传统医药》2024年第6期148-153,共6页Asia-Pacific Traditional Medicine

基　　金：天津市中医药管理局中西医结合科研课题(2021117)。

摘　　要：目的:比较《伤寒论》柴胡剂在现代临床各类疾病中的应用,分析柴胡剂临床使用的特点与依据。方法:基于中国知网(CNKI)平台,检索近5年《伤寒论》柴胡剂的临床应用相关文献,进行分类、归纳、统计,并结合不同疾病的特点分析柴胡剂的现代临床应用。结果:共检索文献2 076篇,纳入研究1 458篇,应用于外感类疾病有101篇,涉及杂病有1 357篇。主要涉及的疾病分类依次为消化系疾病、神经精神疾病、心血管疾病、内分泌疾病、呼吸系疾病、肿瘤疾病、儿科疾病、妇科疾病等。小柴胡汤在消化系疾病(24.03%)、呼吸系疾病(19.33%)中使用频率最高,在呼吸系疾病的使用显著高于其他柴胡剂,文献115篇;大柴胡汤在消化系疾病(55.23%)、内分泌疾病(13.40%)中使用最多,在消化系疾病的使用显著高于其他柴胡剂,文献169篇;柴胡桂枝汤在神经精神疾病中使用最多,占比21.33%;柴胡桂枝干姜汤在消化系疾病中使用最多,占比33.57%;柴胡加龙骨牡蛎汤在神经精神(53.33%)、心血管疾病(23.19%)中使用最多,文献数分别为184篇、80篇,均高于其他柴胡剂;四逆散在消化系疾病(55.36%)、神经精神类疾病(14.59%)中使用最多,在消化系疾病的使用比例高于其他柴胡剂。结论:《伤寒论》柴胡剂的现代临床应用已不局限于外感疾病,因病机类似可广泛应用于杂病治疗。柴胡剂在不同类型疾病的应用存在明显差异,故仍具有探索其病机异同以及拓展临床应用范围等价值。Objective:To compare the modern clinical applications of Bupleurum decoctions of Treatise on Febrile Diseases in various diseases,and to analyze the characteristics and basis of the clinical application of Bupleurum decoctions.Methods:Based on the CNKI,retrieve the related literature on the clinical application of Bupleurum decoctions of Treatise on Febrile Diseases in the past five years.Then classify,summarize,and count it.Analyze the modern clinical application of Bupleurum decoction with the characteristics of different diseases.Results:A total of 2 076 articles were retrieved,and then 1 458 articles were included.101 articles were applied to exogenous diseases and 1 357 articles involved miscellaneous diseases.The main disease classifications involved in order were digestive diseases,neuropsychiatric diseases,cardiovascular diseases,endocrine diseases,respiratory diseases,tumor diseases,pediatric diseases,gynecological diseases,etc.Minor Bupleurum decoction was most used in digestive(24.03%) and respiratory diseases(19.33%),and its use in respiratory diseases was significantly higher than that of other Bupleurum Decoctions,115 articles in total.Major Bupleurum decoction was most used in digestive(55.23%) and endocrine diseases(13.40%),and its use in digestive diseases was significantly higher than that of other Bupleurum decoctions,169 articles in total.Bupleurum decoction with Guizhi was most used in neuropsychiatric diseases,accounting for 21.33%.Bupleurum guizhi decoction with dried ginger was most used in digestive diseases,accounting for 33.57%.Bupleurum Longgu Oyster Decoction was most used in neuropsychiatric(53.33%) and cardiovascular diseases(23.19%),with 184 and 80 articles in total,respectively,both higher than other Bupleurum decoctions.Sini Powder was most used in digestive(55.36%) and neuropsychiatric diseases(14.59%),and its proportion in digestive diseases was significantly higher than that of other Bupleurum decoctions.Conclusion:The modern clinical application of Bupleurum decoctions in the

关 键 词：柴胡剂 《伤寒论》 临床研究 比较研究 方证 

分 类 号：R222[医药卫生—中医基础理论]