Differential distribution of fibrovascular proliferative membranes in 25-gauge vitrectomy for proliferative diabetic retinopathy  

作　　者：Nan Lu Shi-Lin Yang Shuo Guo Dong-Ni Yang Li Liu Chun-Hui Fan Ying Guo Jian Liu Wei Zhao 

机构地区：[1]Department of Ophthalmology,the First Hospital of Qinhuangdao,Qinhuangdao 066000,Hebei Province,China [2]School of Control Engineering,Northeastern University at Qinhuangdao,Qinhuangdao 066004,Hebei Province,China

出　　处：《International Journal of Ophthalmology(English edition)》2024年第8期1462-1468,共7页国际眼科杂志（英文版）

基　　金：Supported by the Program for Qinhuangdao Self-financing Science and Technology Plan of 2008 (No.201805A143).

摘　　要：AIM:To analyze the distribution of fibrovascular proliferative membranes(FVPMs)in proliferative diabetic retinopathy(PDR)patients that treated with pars plana vitrectomy(PPV),and to evaluate the outcomes separately.METHODS:This was a retrospective and cross-sectional study.Consecutive 25-gauge(25-G)PPV cases operated for PDR from May 2018 to April 2020.According to the FVPMs images outlined after operations,subjects were assigned into three groups:arcade type group,juxtapapillary type group,and central type group.All patients were followed up for over one year.General characteristics,operation-related variables,postoperative parameters and complications were recorded.RESULTS:Among 103 eyes recruited,the FVPMs distribution of nasotemporal and inferiosuperioral was significantly different(both P<0.01),with 95(92.23%)FVPMs located in the nasal quadrants,and 74(71.84%)in the inferior.The eyes with a central FVPM required the longest operation time,with silicon oil used in most patients,generally combined with tractional retinal detachment(RD)and rhegmatogenous RD,the worst postoperative bestcorrected visual acuity(BCVA)and the highest rates of recurrent RD(all P<0.05).FVPM type,age of onset diabetes mellitus,preoperative BCVA,and combined with tractional RD and rhegmatogenous RD were significantly associated with BCVA improvement(all P<0.05).Compared with the central type group,the arcade type group had higher rates of BCVA improvement.CONCLUSION:FVPMs are more commonly found in the nasal and inferior mid-peripheral retina in addition to the area of arcade vessels.Performing 25-G PPV for treating PDR eyes with central FVPM have relatively worse prognosis.

关 键 词：proliferative diabetic retinopathy fibrovascular proliferative membrane 25-gauge pars plana vitrectomy 

分 类 号：R779.6[医药卫生—眼科]