Visible-light photoredox-catalyzed carboxylation of aryl epoxides with CO_(2)  

作　　者：Tian-Yu Gao Xiao-Yan Mo Shu-Rong Zhang Yuan-Xu Jiang Shu-Ping Luo Jian-Heng Ye Da-Gang Yu 

机构地区：[1]Key Laboratory of Green Chemistry&Technology of Ministry of Education,College of Chemistry,Sichuan University,Chengdu 610064,China [2]State Key Laboratory Breeding Base of Green Chemistry-Synthesis Technology,Zhejiang University of Technology,Hangzhou 310014,China [3]State Key Laboratory of Elemento-Organic Chemistry,Nankai University,Tianjin 300071,China

出　　处：《Chinese Chemical Letters》2024年第7期281-284,共4页中国化学快报（英文版）

基　　金：the National Natural Science Foundation of China (Nos. 22225106, 22301193);Fundamental Research Funds from Sichuan University (No. 2020SCUNL102);the Fundamental Research Funds for the Central Universities。

摘　　要：Herein, we report the first visible-light photoredox-catalyzed carboxylation of aryl epoxides with CO_(2)to synthesize hydroxy acid derivatives. A variety of valuable β-, γ-, δ-, ε–hydroxy acid derivatives are obtained in moderate to high yields under mild conditions. This protocol shows noteworthy functionalgroup compatibility, high chemo-and regioselectivities under transition-metal-free conditions with an inexpensive organo-dye as photosensitizer. Mechanistic studies indicate that the benzylic carbanion is generated as an intermediate via the sequential single electron transfer(SSET) process.

关 键 词：Carbon dioxide EPOXIDES Visible-light photoredox catalysis Hydroxy acid Sequential single electron transfer 

分 类 号：O621.251[理学—有机化学]